We describe profile of 60 children [mean (SD) age, 9.5 (3.8) y] presenting to the department of Pediatrics with snake envenomation. Neurotoxic bites were predominant (53%) and required mean (SD) 21.5 (9.29) antisnake venom vials, while children with neurohemotoxic features required mean (SD) 31.2 (10.8) vials to improve. Duration of hospital stay was median (SD) 4.0 (2.71) days. The commonest complication was respiratory dysfunction; mortality rate was 13.3%.
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Int J Public Health
January 2025
School of Public Health, Hainan Medical University, Haikou, Hainan Province, China.
Objectives: To analyze the spatial accessibility of antivenom immunizing agents equipped hospitals in Hainan Province.
Methods: This paper analyzes the spatial accessibility of medical institutions equipped with different types of snake antivenom using network analysis and two-step mobile search method, and evaluates the service level and spatial accessibility of medical institutions equipped with different types of antivenom immunizing agents in Hainan Province from the perspectives of both supply and demand.
Results: The number of people in Hainan Province who need to spend more than 1 h to reach an antivenom, antivenom, antivenom, antivenom equipped hospital, and equipped with antivenom for all species of snakes in the country is approximately 856,000, 231,300, 3,071,000, 2,666,000 and 4,721,000 people, respectively.
Scientists are turning to AI to make antivenoms cheaper, faster, and more effective.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Immunochemistry Laboratory, Butantan Institute, São Paulo, SP, Brazil; Center of Toxins, Cell Signaling and Immune Response (CeTICS), CEPID, FAPESP, Brazil. Electronic address:
The complement system plays a crucial role in various pathophysiological conditions, including snake envenomation. In this study, we investigated the effects of Bitis arietans venom on the complement system using an ex vivo human whole blood model. Our findings demonstrate that B.
View Article and Find Full Text PDFBMJ Open
December 2024
Department of Pharmacology, University of Pretoria, Pretoria, South Africa.
Introduction: Snakebite envenomation has been declared a neglected tropical disease by the WHO since 2017. The disease is endemic in affected areas due to the lack of availability and access to antivenom, despite it being the standard treatment for snakebites. This challenge is perpetuated by the shortcomings of the regulatory systems and policies governing the management of antivenoms.
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