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Detecting somatic single nucleotide variants (SNVs) is an essential component of cancer research with next generation sequencing data. This protocol describes how to run the SomaticSniper somatic SNV detector and then filter the output to eliminate most false positives. It also includes support protocols detailing the compilation of the software.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242521PMC
http://dx.doi.org/10.1002/0471250953.bi1505s45DOI Listing

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