This article provides a summary of the changes in lung transplantation after implementation of the Lung Allocation Score in 2005. Specific issues that are addressed include impact of diagnosis group, age, critical illness, and geographic disparities in transplant.
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http://dx.doi.org/10.1016/j.thorsurg.2014.09.001 | DOI Listing |
JTCVS Open
December 2024
Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC.
Objective: Racial disparities in organ allocation may result in differential survival for marginalized groups. This study aims to examine the impact of the November 2017 lung allocation policy change (LAPC) on trends and outcomes of Hispanic lung transplant (LT) recipients.
Methods: The United Network for Organ Sharing database was used to identify adult (older than age 18 years) LT recipients between January 2010 and March 2023.
J Toxicol Environ Health A
January 2025
Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Microcystin-LR (MC-LR) a cyclic toxin produced by cyanobacterial species is known to exert detrimental effects on various organs, including lung. Several investigators demonstrated that MC-LR exerts pulmonary toxicity, but the underlying mechanisms remain unclear. This study aimed to investigate whether exposure to MC-LR-induced lung inflammation and examine the underlying mechanisms.
View Article and Find Full Text PDFHeart Lung
January 2025
Division of Cardiac Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada. Electronic address:
Background: The coronavirus disease 2019(COVID-19) pandemic significantly impacted the lives of patients and healthcare professionals globally. With rapid spread and severe illness, a great deal of healthcare resources including personal, funding, and hospital beds were dedicated to fight the pandemic.
Objectives: This survey looks to characterize how resources were allocated among Canadian cardiac surgery programs, and how this impacted patient care and outcomes.
Lung Cancer
January 2025
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing 210029, China. Electronic address:
Neuron-specific enolase (NSE) is one of the most common biomarkers of small cell lung cancer (SCLC) and is widely used in lung cancer screening. But its specificity is affected by many factors. Using residual correction and machine learning, corrected NSE and its reference range were constructed based on metabolic factors and smoking history affecting NSE in the training set of 48,009 healthy individuals recruited from the First Affiliated Hospital of Nanjing Medical University.
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