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Relationship between platelet-to-lymphocyte ratio and coronary slow flow. | LitMetric

AI Article Synopsis

  • The study investigates the relationship between the platelet-to-lymphocyte ratio (PLR) and coronary slow flow phenomenon (CSFP), which occurs without major artery blockages.
  • Researchers conducted a retrospective study involving 197 patients, dividing them into those with CSFP and those with normal coronary flow.
  • Results indicated that patients with CSFP had significantly higher PLR levels, suggesting a strong independent correlation between elevated PLR and the occurrence of CSFP.

Article Abstract

Objective: The coronary slow flow phenomenon (CSFP), which is characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease, is an angiographic finding. The aim of this study is to investigate the association between platelet-to-lymphocyte ratio (PLR) and coronary blood flow rate.

Methods: This is a retrospective observational study. It was based on two medical centers. A total of 197 patients undergoing coronary angiography were included in the study, 95 of whom were patients with coronary slow flow without stenosis in coronary angiography and 102 of whom had normal coronary arteries and normal flow.

Results: The PLR was higher in the coronary slow flow group compared with the control groups (p=0.001). In the correlation analysis, PLR showed a significant correlation with left anterior descending (LAD) artery thrombolysis in myocardial infarction (TIMI) frame count. After multiple logistic regression, high levels of PLR were independently associated with coronary slow flow, together with hemoglobin.

Conclusion: PLR was higher in patients with CSFP, and we also showed that PLR was significantly and independently associated with CSFP.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779176PMC
http://dx.doi.org/10.5152/akd.2014.5376DOI Listing

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