Two cases of tuberculosis of the patella presenting as an osteolytic lesion with sequestrum are described. Timely diagnosis helped in successful management of both these cases, resulting in complete resolution of symptoms with a functional knee without need for patellectomy. Clinicians must consider the possibility of diagnosis of isolated patellar tuberculosis in patients presenting with an osteolytic lesion in patella especially in areas where tuberculosis is endemic and in immunocompromised patients.
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