Chemotherapy treatment recommendations traditionally have been based on the anatomic site of origin and the histology of the tumor. More recently, treatment options are transitioning to targeted therapies, in which drug selection is based on mutations present in an individual tumor. Genomic testing is a developing area that involves testing tumors to determine their molecular or genetic characteristics, then matching those characteristics to treatments that specifically target them.
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http://dx.doi.org/10.1188/14.CJON.717-718 | DOI Listing |
BMC Public Health
January 2025
King's Centre for Military Health Research, King's College London, London, SE5 9RJ, UK.
Background: The coronavirus disease (COVID-19) pandemic led to the implementation of social distancing laws in the UK. This had several negative consequences on health, wellbeing and social functioning within the general population. Military veterans may have had unique experiences of social isolation during this time.
View Article and Find Full Text PDFAppl Psychophysiol Biofeedback
January 2025
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, No.28, Xianning West Road, Xi'an, Shaanxi, 710049, P. R. China.
Resonance frequency (RF) is characterized as the specific frequency at which a system, equipped with delayed self-correction or negative feedback mechanisms, exhibits maximal amplitude oscillations in response to an external stimulus of a particular frequency. Emerging evidence suggests that the cardiovascular system has an inherent RF, and that breathing at this frequency can markedly enhance health and cardiovascular function. However, the efficacy of resonance frequency breathing (RFB) and the specific responses of the cardiovascular, respiratory, and central nervous systems during RFB remain unclear.
View Article and Find Full Text PDFAdv Mater
January 2025
Laboratory of Advanced Materials, Institute of Optoelectronics, Fudan University, Shanghai, 200438, P. R. China.
Metal single atoms (SA)-support interactions inherently exhibit significant electrochemical activity, demonstrating potential in energy catalysis. However, leveraging these interactions to modulate electronic properties and extend application fields is a formidable challenge, demanding in-depth understanding and quantitative control of atomic-scale interactions. Herein, in situ, off-axis electron holography technique is utilized to directly visualize the interactions between SAs and the graphene surface.
View Article and Find Full Text PDFSci Rep
January 2025
School of Physics and Optoelectronic Engineering, Key Laboratory of Gravitational Wave Precision Measurement of Zhejiang Province, Taiji Laboratory for Gravitational Wave Universe, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China.
In this paper, a fixed support method for a cryogenic monocrystalline silicon Fabry-Pérot cavity of an ultra-stable laser for space applications is proposed. Through finite element analysis, the vibration sensitivity at the center of the cavity is below 10E-12/g; the fundamental frequency is 381 Hz; the thermal deformation is compensated by applying a preload force of about 3 N*m for a variation of 300 K to 124 K. Based on these analyses, an equal-mass cavity simulator was machined and mounted.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Instituto de Telecomunicações, University of Aveiro, 3810-193 Aveiro, Portugal.
As the demand for high-speed, low-latency communication continues to grow, free-space optical (FSO) communication has gained prominence as a promising solution for supporting the next generation of wireless networks, especially in the context of the 5G and beyond era. It offers high-speed, low-latency data transmission over long distances without the need for a physical infrastructure. However, the deployment of FSO systems faces significant challenges, such as atmospheric turbulence, weather-induced signal degradation, and alignment issues, all of which can impair performance.
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