Background: Waist-to-height ratio (WHtR) is a cardiometabolic risk indicator in children. A value greater than or equal to 0.55 is an effective screening tool for identifying obese children with metabolic syndrome. However, it is unclear whether this cutoff can be applied equally to any age or gender.
Aim: To analyze the variability of WHtR by age, gender and pubertal stage in elementary school children.
Patients And Methods: Cross-sectional study in 2,980 school children (6-14 years old, 51% male) of Santiago, Chile. We measured weight, height and waist circumference and calculated body mass index and WHtR. Pubertal stage was assessed and classified as peripubertal (Tanner I and II) and pubertal (Tanner III, IV and V).
Results: The mean age was 9.9 ± 2.3 years, with no gender difference (p = 0.5). Eighty one percent of boys and 59.4% of girls were peripubertal (p < 0.001). The association between age-adjusted WHtR by gender and pubertal stage was not significant (p = 0.409). Therefore mean, standard deviation and percentiles of WHtR were calculated without sex and pubertal stage segmentations.
Conclusions: Since WHtR does not vary with age, gender and pubertal status in elementary school children, it is possible to use a single cutoff value, previously defined in this population, to identify children with cardiometabolic risk.
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http://dx.doi.org/10.4067/S0034-98872014000500004 | DOI Listing |
Pediatr Diabetes
December 2024
Department of Pediatrics, Division of Pediatric Endocrinology, University of Michigan, Ann Arbor, USA.
Context: Insulin sensitivity and secretion indices can be useful tools in understanding insulin homeostasis in children at risk for diabetes. There have been few studies examining the reproducibility of these measures in pediatrics.
Objective: To determine whether fasting or oral glucose tolerance test (OGTT)-derived insulin measures would be more reproducible and whether there would be differences based on weight, sex, race, and pubertal status.
Lipids Health Dis
December 2024
Department of Epidemiology and Health Monitoring, Robert Koch-Institute Berlin, Berlin, Germany.
Background: Universal lipid screening in childhood for early detection and treatment of familial hypercholesterolemia is under discussion, but will also detect children with multifactorial dyslipidemia. Results from population-based studies can support the design of public health strategies. As few previous studies considered pubertal changes in serum lipid levels, we examined tracking of serum lipids from prepuberty to young adulthood in a population-based cohort.
View Article and Find Full Text PDFDiabetes Res Clin Pract
December 2024
Department of Pediatrics, Division of Molecular Genetics, Columbia University Irving Medical Center, New York, NY, United States. Electronic address:
Aims: This study examined the association of gravida C-peptide with progeny islet function and insulin sensitivity in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS).
Methods: Pregnancy 3rd trimester oral glucose tolerance test (OGTT), cord blood, and offspring OGTT glucose, C-peptide and insulin at age 10-14 years were analyzed for 4,121 mother-child dyads. Gravida fasting and 1-hour C-peptide concentration correlations with cord blood and childhood C-peptide, insulin, insulinogenic index and insulin sensitivity, and insulin resistance [HOMA-IR]), were assessed by multiple linear regression.
Dental Press J Orthod
December 2024
Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Patologia e Diagnóstico Oral (Rio de Janeiro, RJ, Brazil).
Introduction: The early diagnosis of mandibular asymmetry (MA) in patients with unilateral cleft lip and palate (UCLP) can contribute to its treatment.
Objective: The aim of this study was to evaluate the occurrence and the extent of MA in UCLP patients at different growth stages.
Methods: Cone-beam computed tomography (CBCT) of 47 UCLP patients were included, and divided into two groups (prepubertal stage and pubertal stage).
Environ Res
December 2024
Institut de recherche en santé, environnement et travail (Irset), Univ Rennes, Inserm, EHESP, 9 Av. Professeur Léon Bernard, Rennes, France. Electronic address:
Introduction: While a number of studies have examined the effects of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on childhood obesity, the results reported have been inconsistent and few studies have integrated biological markers. The aim of this study was to investigate the associations between prenatal exposure to PFAS and cardiometabolic health parameters at age 12, taking pubertal stage into consideration.
Method: This study included 394 mother-child pairs enrolled in the PELAGIE mother-child cohort (France).
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