Toothbrush, the innocent cleaning aid, has been reported to cause life threatening oropharyngeal injuries in pediatric literature. A case of a 4-year-old child reporting to an emergency department with a toothbrush impaled in her mouth while her father was forcefully brushing her teeth is reported here. Hemostasis was achieved by digital pressure and the impaled toothbrush was removed surgically. Uneventful recovery was noted. Parental anxiety and a lack of patient cooperation was noted. Such impaled objects fractured and left behind have been reported to cause serious space infections and mediastinitus. Advising parents to be careful with their children's toothbrush is important as prevention of injuries from such commonly used object could be easily achieved.
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http://dx.doi.org/10.1111/j.2041-1626.2010.00002.x | DOI Listing |
Forensic Sci Med Pathol
January 2025
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Nitrous oxide (NO) abuse is becoming increasingly popular worldwide. Moreover, the use of NO combined with other substances, such as alcohol, is also common. Accidental deaths associated with NO abuse are rare in forensic practice, with most fatal cases involving continuous inhalation equipment or exposure in a confined space.
View Article and Find Full Text PDFFront Cell Dev Biol
January 2025
Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, Essen, Germany.
Consolidation with PD-1/PD-L1-based immune checkpoint blockade after concurrent platinum-based chemo-radiotherapy has become the new standard of care for advanced stage III unresectable non-small cell lung cancer (NSCLC) patients. In order to further improve therapy outcomes, innovative combinatorial treatment strategies aim to target additional immunosuppressive barriers in the tumor microenvironment such as the CD73/adenosine pathway. CD73 and adenosine are known as crucial endogenous regulators of lung homeostasis and inflammation, but also contribute to an immunosuppressive tumor microenvironment.
View Article and Find Full Text PDFPediatrics
January 2025
Johns Hopkins University, Baltimore, Maryland.
Water beads are superabsorbent polymer balls. They were originally marketed for agricultural and decorative applications and are now sold as sensory toys. They can be harmful to children in 2 ways.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Electrical and Electronic Engineering, Pabna University of Science and Technology, Pabna, Bangladesh.
Waterborne bacteria pose a serious hazard to human health, hence a precise detection method is required to identify them. A photonic crystal fiber sensor that takes into account the dangers of aquatic bacteria has been suggested, and its optical characteristics in the THz range have been quantitatively assessed. The PCF sensor was designed and examined as computed in Comsol Multiphysics, a program in which uses the method of "Finite Element Method" (FEM).
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