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A new phenylpropanoid from the roots of Euphorbia nematocypha. | LitMetric

A new phenylpropanoid from the roots of Euphorbia nematocypha.

Nat Prod Res

a Department of Pharmaceutical Engineering , School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189 , PR China.

Published: June 2015

AI Article Synopsis

  • - A study on the ethanolic extracts from the roots of Euphorbia nematocypha led to the discovery of a new compound called 16-O-caffeoyl-16-hydroxylhexadecanoic acid (1), along with 23 other known compounds (2-24).
  • - The chemical structures of these compounds were identified using spectroscopic methods.
  • - The newly identified phenylpropanoid demonstrated strong cytotoxic effects against breast cancer (MCF-7) and cervical cancer (HeLa) cell lines.

Article Abstract

A phytochemical investigation of the ethanolic extracts of the dried roots of Euphorbia nematocypha resulted in the isolation of a new phenylpropanoid, 16-O-caffeoyl-16-hydroxylhexadecanoic acid (1), together with 23 known compounds (2-24). Their structures were elucidated on the basis of spectroscopic data. Compound 1 was first to be isolated as a caffeic acyl long chain alkyl acid from the family Euphorbiaceae. The new isolated phenylpropanoid showed potent cytotoxic activities against the MCF-7 and HeLa cell lines.

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Source
http://dx.doi.org/10.1080/14786419.2014.980256DOI Listing

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