The survival of developing embryos depends on the control and maintenance of homeostasis. Stress caused by chronic immobilization during pregnancy in rats may alter the normal development of the nervous system and increase susceptibility to psychiatric disorders. We investigated the effects of chronic stress on cell proliferation in the forebrains of embryos at 12 days of gestation, and in the hippocampus, dentate gyrus and cortex in embryos at 17 and 21 days of gestation. We examined serial sections of the embryonic brains of control and stressed rats at days 12, 17 and 21 of gestation. Brain sections were immunolabeled with anti-PCNA and stereological analysis was performed on 540 images. The results showed no statistical differences on days 12 and 17 of gestation in the proliferation area of the structures studied, whereas on day 21 of gestation, proliferation decreased in the cortex and dentate gyrus of embryos of the stressed group. These changes were related to decreased prolactin and increased corticosterone concentrations in the plasma.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/10520295.2014.976269 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A retrospective case-control study of pregnancy failure in Thoroughbred horses in Australia.
Prev Vet Med
January 2025
Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, NSW 2006, Australia; Sydney Infectious Diseases Institute, The University of Sydney, Camperdown, NSW 2006, Australia. Electronic address:
Pregnancy failure is a serious economic and welfare concern in the Thoroughbred horse industry, yet its incidence and risk factors in Australia remain unclear. This retrospective, nested, case-control study investigated pregnancy failure in resident mares on studs in the Hunter Valley, Australia, in 2021-2022, in early (46-150 days), mid (151-270 days), and late (>270 days) gestation. We found an annual incidence risk of 5.
View Article and Find Full Text PDFUncommon unilateral congenital knee dislocation. A case report.
Int J Surg Case Rep
January 2025
Department of Radiology, Mehal Meda Hospital, Mehal Meda, Ethiopia.
Introduction And Importance: The estimated incidence of congenital dislocation of the knee, also referred to as genu recurvatum, is approximately 1 in 100,000 live births. The purpose of this report is to present a rare case of unilateral congenital knee dislocation, highlighting the clinical presentation and management.
Case Presentation: A 9-day-old female infant was born to a 30-year-old primigravida mother following an uncomplicated term pregnancy of 39 weeks and 4 days.
Research on the application effect of self-transcendence nursing model in patients with gestational diabetes mellitus: a randomised controlled trial.
BMC Pregnancy Childbirth
January 2025
Editorial Board of Jiangsu Medical Journal, the First Affiliated Hospital With Nanjing Medical University, Nanjing, 210029, China.
Background: Gestational diabetes mellitus is hyperglycemia in special populations (pregnant women), however gestational diabetes mellitus (GDM) not only affects maternal health, but also has profound effects on offspring health. The prevalence of gestational diabetes in my country is gradually increasing.
Objective: To study the application effect of self-transcendence nursing model in GDM patients.
Clinical value of quantitative echocardiographic features in preterm infants with necrotizing enterocolitis.
Sci Rep
January 2025
Department of Neonatology, Children's Hospital of Soochow University, Suzhou, China.
This study investigated the correlation between quantitative echocardiographic characteristics within 3 days of birth and necrotizing enterocolitis (NEC) and its severity in preterm infants. A retrospective study was conducted on 168 preterm infants with a gestational age of < 34 weeks. Patients were categorized into NEC and non-NEC groups.
View Article and Find Full Text PDFBladder rupture in late-pregnancy mares: Four cases.
J Equine Vet Sci
January 2025
Clinique Vétérinaire Équine du Harfang, Varennes, Quebec, Canada.
This case series reports four late pregnancy broodmares that were diagnosed with bladder rupture. The initial presentations were abdominal discomfort (n = 3) and dystocia (n = 1). All mares (n = 4) were overdue or at their expected time of delivery.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!