AI Article Synopsis
- Dobutamine can be an unrecognized cause of eosinophilic myocarditis (EM), which can lead to severe clinical worsening in patients.
- Patients with end-stage cardiomyopathy are particularly vulnerable, as their hearts have limited capacity to handle stress, potentially necessitating mechanical support.
- A case study highlights a man with dilated cardiomyopathy who experienced rapid deterioration due to dobutamine-induced EM, requiring urgent treatment, which improved after stopping the medication.
Article Abstract
Dobutamine is a rare and unrecognized cause of eosinophilic myocarditis (EM). It is even more unique for it to cause significant clinical deterioration. Patients with end stage cardiomyopathy have very little cardiac reserve and dobutamine induced myocarditis may cause enough harm to require urgent mechanical circulatory support. We describe a man with dilated cardiomyopathy that developed accelerated clinical deterioration from dobutamine induced EM. He had a predominance of right heart failure, requiring an urgent biventricular assist device and acutely responded to withdrawal of dobutamine.
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| http://dx.doi.org/10.1097/MAT.0000000000000175 | DOI Listing |
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