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| http://dx.doi.org/10.11604/pamj.2014.18.132.4091 | DOI Listing |
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The elusive bipartite scaphoid: a rare congenital variant or misdiagnosed pseudoarthrosis? A proposal for novel radiological criteria.
Folia Morphol (Warsz)
January 2025
Department of Orthopedics and Traumatology, University Hospital Queen Giovanna-ISUL, Medical University of Sofia, Sofia, Bulgaria.
Variations in the development of carpal bones are uncommon, with the scaphoid bone typically forming from the fusion of the os centrale carpi and the radial chondrification center during embryogenesis. A bipartite scaphoid is a rare congenital disorder that occurs when these ossification centers fail to fuse, with a prevalence ranging from 0.1% to 0.
View Article and Find Full Text PDFMultigenerational effects of individual and binary mixtures of two commonly used NSAIDs on Daphnia carinata.
Ecotoxicology
January 2025
Ecotoxicology Research group, School of Science, RMIT University, Melbourne, VIC, Australia.
Pharmaceuticals, including non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (IBU) and naproxen (NPX), are widely used for medical purposes but have also become prevalent environmental contaminants. However, there is limited understanding of their effects on aquatic organisms, especially regarding multigenerational and mixture exposures. This study aimed to evaluate the toxicological impacts of ibuprofen and naproxen, individually and in combination, on three generations of Daphnia carinata, a freshwater organism.
View Article and Find Full Text PDFIntroduction: The relationship between the phenotype and treatment of psoriatic arthritis (PsA) and the increased prevalence of cardiovascular comorbidities is not well studied.
Objective: To assess the prevalence of cardiovascular comorbidities in relation to the clinical phenotype and treatment of PsA.
Methods: This was a cross-sectional, real-life study.
Associating regulatory actions on diclofenac use with Danish trends in utilization by route of administration 1999-2023.
Pharmacotherapy
January 2025
Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Aims: With the growing evidence of cardiovascular risks associated with diclofenac use, regulatory measures governing its application and sales have intensified since 2008. We evaluated the association between central regulatory actions and trends in diclofenac use in Denmark from 1999 to 2023, according to different dosage forms and routes of administration.
Methods And Results: Data on diclofenac sales in Denmark from 1999 to 2023 were retrieved from the publicly available web database MEDSTAT, based on the Danish Register of Medicinal Products Statistics.
Clinical characteristics and prognostic factors of COVID-19 in rheumatic patients and their family members: a retrospective study.
Front Immunol
January 2025
Department of Rheumatism and Immunity, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Article Synopsis
- Patients with rheumatic diseases tend to recover from COVID-19 faster (average 13 days) compared to their family members (average 16 days), despite being on immunosuppressive treatments.
- The study found that rheumatic patients have a lower risk of developing moderate to severe COVID-19, with pre-infection use of NSAIDs linked to a higher chance of mild cases.
- Patients using disease-modifying anti-rheumatic drugs (DMARDs) before infection were significantly less likely to develop severe cases compared to those who were not on these medications.
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