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Pustular and crusted lesions in systemic lupus erythematosus: A case report.
J Family Med Prim Care
November 2024
Department of Dermatology, Venereology and Leprosy, SRM Medical College and Research Centre, Chengalpattu, Tamil Nadu, India.
Systemic lupus erythematosus (SLE) is the prototype of an autoimmune disease with various manifestations in the skin and several other organs. Subacute cutaneous lupus erythematosus may present with annular and psoriasiform lesions. There have been case reports of pustular lesions in SLE.
View Article and Find Full Text PDFDrug-Associated Risk of Subacute Cutaneous Lupus Erythematosus: A Pharmacovigilance Study of the FDA Adverse Event Reporting System.
J Cutan Med Surg
December 2024
Department of Dermatology, Guanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
[Systemic lupus erythematosus involving the fornix column leading to hyponatremia: A case report].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Rheumatology, Peking University Third Hospital, Beijing 100191, China.
We reported the diagnostic and therapeutic process of a young male patient with systemic lupus erythematosus (SLE) who presented with severe hyponatremia as the main manifestation upon admission, and analyzed and discussed the case. The patient was a 19-year-old young male with a subacute course of disease, fever ≥38.3 ℃ that could not be explained by other causes, acute and subacute cutaneous lupus erythematosus, oral ulcers, arthritis, leukopenia (< 4×10/L), low C3+low C4, and positive anti-double-stranded DNA (anti-dsDNA).
View Article and Find Full Text PDFA review on toxic epidermal necrolysis-like superficial wound lesions: Issue and challenge on 10 clinical entities.
Int Wound J
December 2024
Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Toxic epidermal necrolysis (TEN) is a severe skin reaction caused by extensive epidermal and mucosal necrosis. This clinical phenomenon is known as an acute syndrome of apoptotic pan-epidermolysis (ASAP). The ASAP phenomenon is observed in conditions that mimic TEN, highlighting the challenge in distinguishing these conditions.
View Article and Find Full Text PDFArticle Synopsis
- Cutaneous lupus erythematosus (CLE) is a skin-related manifestation of lupus erythematosus, classified into subtypes (acute, subacute, chronic) based on clinical characteristics and lab findings.
- Traditional treatments include topical corticosteroids and antimalarial drugs, but new immunomodulatory therapies, particularly Janus kinase (JAK) inhibitors, are emerging options.
- The review highlights the importance of understanding the JAK/STAT signaling pathway in CLE management and calls for more research on the safety and effectiveness of JAK inhibitors for autoimmune disease treatment.
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