Introduction: Hypertension among African Americans is higher compared to Whites and has an early onset, greater severity, and is associated with more organ damage. We examined whether pharmaceutical treatment of hypertension among underserved African American elderly is consistent with the current treatment guidelines and whether treatment variations occur due to existing co-morbidities among the hypertensive.
Methods: Our study surveyed 400 African Americans, aged ≥ 65 years, recruited from 16 predominantly African American churches located in South Los Angeles. The study used face-to-face interviews which documented type, frequency, and dosage of all medications used by participants. Label information of each drug was recorded.
Results: Our data indicate: 1) 29% were on one anti-hypertensive medication; 60% were taking 2-3 medications; and 9% were on four classes of anti-hypertensive medication; 2) among the elderly taking a combination of two or more drugs, ACE or ARB was used 76% in combination of agents, diuretics 60%, calcium channel blockers 63%, and beta-blocker 61%; and 3) 26% of the elderly were taking ≥ 3 medications including a diuretic.
Conclusions: Treatment of hypertension appears to be inconsistent with the prevailing treatment guidelines for nearly one-third of the aged African Americans. Further investigation is needed to determine why a significant number of individuals from this under-served population are not receiving care based on established clinical guidelines.
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J Clin Psychiatry
January 2025
Psychotic Disorders Division, McLean Hospital, Belmont, Massachusetts.
Individuals with severe mental illness (SMI) have a shorter life expectancy compared to the general population, largely due to cardiovascular disease (CVD). In this report from the Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients (FITNESS), we examined baseline CVD risk factors and their treatment in patients with SMI and second generation antipsychotic (SGA) use. FITNESS enrolled 204 participants with SMI and SGA use, but without documented history of CVD or diabetes mellitus, from several clinics in the Boston, Massachusetts, area between April 29, 2015, and September 26, 2019.
View Article and Find Full Text PDFGac Med Mex
January 2025
División de Obstetricia. Unidad Médica de Alta Especialidad Hospital de Gineco-Obstetricia 4 "Luis Castelazo Ayala", Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Introduction: Twin pregnancy through assisted reproduction techniques is increasing, as are the associated complications.
Objective: Compare maternal and perinatal complications associated with spontaneous twin pregnancy and through assisted reproduction techniques (ART).
Material And Methods: Retrospective comparative and controlled study.
J Neurosurg Case Lessons
January 2025
Neurosurgery Department, Palmetto General Hospital, Hialeah, Florida.
Background: Astroblastoma is an extremely rare tumor of the central nervous system, and its origin and validity as a different entity are still being debated. Because of its rarity and similarities to other glial neoplasms, it is often misdiagnosed, impacting treatment and outcomes.
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Rheumatology (Oxford)
January 2025
Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.
Objectives: To assess the lung involvement in patients with Still's disease, an inflammatory disease assessing both children and adults. To exploit possible associated factors for parenchymal lung involvement in these patients.
Methods: A multicentre observational study was arranged assessing consecutive patients with Still's disease characterized by the lung involvement among those included in the AIDA (AutoInflammatory Disease Alliance) Network Still's Disease Registry.
Interdiscip Cardiovasc Thorac Surg
January 2025
Department of Thoracic Surgery and Heart-Lung Transplantation, Paris-Saclay University, Marie-Lannelongue Hospital, 92350, Le Plessis-Robinson, France.
Objectives: Heparin is given for anticoagulation during and after pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension. Our objective was to add to the limited data available on the incidence, management, and outcomes of suspected heparin-induced thrombocytopaenia after pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension.
Methods: This retrospective single-centre study included consecutive patients with suspected heparin-induced thrombocytopaenia after pulmonary thromboendarterectomy done in 2005-2018.
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