AI Article Synopsis

  • The article reviews literature on aerogenous metastasis, which refers to the spread of cancer through the airways, and discusses its mechanisms, imaging characteristics, and importance in clinical settings.
  • It highlights that aerogenous spread is often overlooked but is supported by cumulative evidence, suggesting a need for greater awareness.
  • Key imaging features can help differentiate aerogenous metastasis from other types of tumor spread and influence staging, treatment decisions, and prognosis for patients with lung cancer.

Article Abstract

Objective: The purposes of this article are to summarize the relevant literature on aerogenous metastasis, explain the putative pathogenetic mechanism of aerogenous spread, present the characteristic imaging and pathologic features, and review the importance of aerogenous spread to staging and clinical management.

Conclusion: Cumulative evidence suggests that aerogenous spread may exist and is underrecognized. Imaging features are helpful in differentiating possible aerogenous spread of tumor from hematogenous and lymphatic metastases and from synchronous primary tumors. The putative occurrence of intrapulmonary aerogenous metastasis of lung cancer has staging, management, and prognostic implications.

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http://dx.doi.org/10.2214/AJR.13.12088DOI Listing

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