Authors present a case of glioblastoma of cerebellum in a 11-year old child. Symptoms and signs are those of other tumors of posterior fossa. Diagnosis was made by CT Scan and pathologist. In spite of radiotherapy, he died one year after craniotomy. Only twenty cases of glioblastoma of cerebellum in childhood were described in the literature.
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Biochim Biophys Acta Mol Basis Dis
January 2025
Department of Chemical and Biological Engineering, Gachon University, 1342 Seongnam Daero, Seongnam-Si, Gyeonggi-Do 13120, Republic of Korea. Electronic address:
Glioblastoma multiforme (GBM) is a highly malignant subtype of glioma, originating from the glial cells that provide support to other neurons in the brain. GBM predominantly impacts the cerebral hemisphere of the brain, with minimal effects on the cerebellum, brain stem, or spinal cord. Individuals diagnosed with GBM commonly encounter a range of symptoms, starting from auditory abnormalities to seizures.
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Univ.Lille, Inserm, CHU Lille, U1192 - Proteomics Inflammatory Response Mass Spectrometry- PRISM, Lille, France; Department Institut Universitaire de France, Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation, Paris, France. Electronic address:
Asian J Pharm Sci
December 2024
Department of Medical Biology, Faculty of Medicine, Bursa Uludag University, Bursa, Turkey.
Total resection of glioblastoma (GB) tumors is nearly impossible, and systemic administration of temozolomide (TMZ) is often inadequate. This study presents a hybrid layered composite nanofiber mesh (LHN) designed for localized treatment in GB tumor bed. The LHN, consisting of polyvinyl alcohol and core-shell polylactic acid layers, was loaded with TMZ and rutin.
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August 2024
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Not all patients with glioblastoma multiforme (GBM) eligible for systemic chemotherapy after upfront surgery and radiotherapy finally receive it. The information on patients with GBM was retrieved from the surveillance, epidemiology, and end results database. Patients who underwent upfront surgery or biopsy and external beam radiotherapy between 2010 and 2019 were eligible for systemic chemotherapy.
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June 2024
One Health Research Group, Universidad de las Americas, Quito 170124, Ecuador.
Glioblastoma is a primary malignant brain tumor; it is aggressive with a high degree of malignancy and unfavorable prognosis and is the most common type of malignant brain tumor. Glioblastomas can be located in the brain, cerebellum, brainstem, and spinal cord, originating from glial cells, particularly astrocytes. The databases MEDLINE, Scopus, Web of Science, Google Scholar, and CINAHL were researched up to January 2024.
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