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The Rising of Flexible Organic Electrochemical Transistors in Sensors and Intelligent Circuits.

ACS Nano

January 2025

College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology), Nanjing University of Posts & Telecommunications (NJUPT), Nanjing 210023, China.

Flexible electronic devices in biomedicine, environmental monitoring, and brain-like computing have garnered significant attention. Among these, organic electrochemical transistors (OECTs) have been spotlighted in flexible sensors and neuromorphic circuits for their low power consumption, high signal amplification, excellent biocompatibility, chemical stability, stretchability, and flexibility. However, OECTs will also face some challenges on the way to commercialized applications, including the need for improved long-term stability, enhanced performance of N-type materials, integration with existing technologies, and cost-effective manufacturing processes.

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The chemistry of the extracellular electron transfer (EET) process in microorganisms can be understood by interfacing them with abiotic materials that act as external redox mediators. These mediators capture and transfer extracellular electrons through redox reactions, bridging the microorganism and the electrode surface. Understanding this charge transfer process is essential for designing biocapacitors capable of modulating and storing charge signatures as capacitance at the electrode interface.

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The primary method of treatment for patients suffering from drug-resistant focal-onset epilepsy is resective surgery, which adversely impacts neurocognitive function. Radio frequency (RF) ablation and laser ablation are the methods with the most promise, achieving seizure-free rates similar to resection but with less negative impact on neurocognitive function. However, there remains a number of concerns and open technical questions about these two methods of thermal ablation, with the primary ones: (1) heating; (2) hemorrhage and bleeding; and (3) poor directionality.

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Vertical organic electrochemical transistors (vOECTs) have received widespread attention in bioelectronics, wearable, and neuromorphic electronics due to their high transconductance (), low driving voltage, and biocompatibility. As key parameters of vOECTs, and switching speed (or transient time, τ) are vital for achieving satisfying performance in various practical applications. Here we employ vOECTs with varying top electrode widths for effective and switching speed modulation.

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An organic electrochemical neuron for a neuromorphic perception system.

Proc Natl Acad Sci U S A

January 2025

Department of Chemistry and the Materials Research Center, Northwestern University, Evanston, IL 60208.

Human perception systems are highly refined, relying on an adaptive, plastic, and event-driven network of sensory neurons. Drawing inspiration from Nature, neuromorphic perception systems hold tremendous potential for efficient multisensory signal processing in the physical world; however, the development of an efficient artificial neuron with a widely calibratable spiking range and reduced footprint remains challenging. Here, we report an efficient organic electrochemical neuron (OECN) with reduced footprint (<37 mm) based on high-performance vertical OECT (vOECT) complementary circuitry enabled by an advanced n-type polymer for balanced p-/n-type vOECT performance.

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