AI Article Synopsis
- Galectins are proteins that bind to galactose and are important in inflammation and cancer growth.
- They help cancer cells thrive by influencing their interactions with their surroundings and weakening the body's ability to fight cancer.
- The review discusses how galectins affect blood-related cancers and suggests they could be useful in developing new treatments for these conditions.
Article Abstract
Galectins are family of galactose-binding proteins known to play critical roles in inflammation and neoplastic progression. Galectins facilitate the growth and survival of neoplastic cells by regulating their cross-talk with the extracellular microenvironment and hampering anti-neoplastic immunity. Here, we review the role of galectins in the biology of hematological malignancies and their promise as potential therapeutic agents in these diseases.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205870 | PMC |
| http://dx.doi.org/10.3978/j.issn.2305-5839.2014.09.14 | DOI Listing |
Publication Analysis
Top Keywords
hematological malignancies
8
galectins
4
galectins therapeutic
4
therapeutic targets
4
targets hematological
4
malignancies hopeful
4
hopeful sweetness
4
sweetness galectins
4
galectins family
4
family galactose-binding
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!