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Breeding sites, migration paths and phylogenetic relationships of mosquitoes in seven cities in northern and southern China.
Trop Biomed
December 2024
NHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199, China.
Mosquito-borne diseases have wreaked havoc on human health, with consequences dramatically increasing in recent years. The incidence of mosquito-borne diseases is closely linked to the locations that are chosen for urban development. The aim of this study was to provide characteristics of mosquito breeding sites in northern and southern China and to document the most important arbovirus vectors found in the study area, the evidence generated here is critical for early prevention and control inter ventions.
View Article and Find Full Text PDFInduction of Antigen-Specific Tolerance in a Multiple Sclerosis Model without Broad Immunosuppression.
ACS Nano
January 2025
Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Multiple sclerosis (MS) is a severe autoimmune disorder that wreaks havoc on the central nervous system, leading to a spectrum of motor and cognitive impairments. There is no cure, and current treatment strategies rely on broad immunosuppression, leaving patients vulnerable to infections. To address this problem, our approach aims to induce antigen-specific tolerance, a much-needed shift in MS therapy.
View Article and Find Full Text PDFEvaluation of a synergistic blend of short- and medium-chain fatty acids as a dietary intervention for the effective management of Vibriosis in shrimp culture.
Fish Shellfish Immunol
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Trouw Nutrition, Nutreco, Amersfoort, the Netherlands.
Vibriosis caused by Vibrio spp. is imposing severe havoc and adverse effects on shrimp culture. Antibiotics are the most widely used therapeutic measures against vibriosis.
View Article and Find Full Text PDFmiR-198 targets : implications for oral squamous cell carcinoma pathogenesis.
Front Oncol
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Department of Developmental Biology and Genetics, Indian Institute of Science, Bangalore, India.
Background: miRNAs play a critical role in the progression of various diseases, including oral squamous cell carcinoma (OSCC), which represents a major health concern and is one of the leading causes for new cancer cases worldwide. The miRNA dysregulation causes havoc and could be attributed to various factors, with epigenetic silencing of tumor suppressor genes being a major contributor to tumorigenesis. In this study, we have explored the tumor suppressive role of miR-198 in OSCC.
View Article and Find Full Text PDFA Glimpse for the subsistence from pandemic SARS-CoV-2 infection.
Bioorg Chem
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School of Pharmaceuticals and Population Health Informatics, Faculty of Pharmacy, DIT University, Dehradun, Uttarakhand, 248009, India.
COVID-19 is an emerging viral pandemic caused by SARS-CoV-2, which is the causative agent of unprecedented disease-causing public health threats globally. Worldwide, this outbreak is wreaking havoc due to failure in risk assessment regarding the urgency of the pandemic. As per the reports, many secondary complications which include neurological, nephrological, gastrointestinal, cardiovascular, immune, and hepatic abnormalities, are linked with COVID -19 infection which is associated with prominent respiratory disorders including pneumonia.
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