Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activity in plant-derived monoterpenes. In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed. Chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220615 | PMC |
| http://dx.doi.org/10.1155/2014/953451 | DOI Listing |
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