Resolution of a giant pigment epithelial detachment after treatment with intravitreal bevacizumab.

Retin Cases Brief Rep

From the Retina Research Fund of St. Mary's Medical Center, San Francisco, and the Pacific Vision Foundation, California Pacific Medical Center, San Francisco, California.

Published: November 2014

Purpose: To describe a patient with a giant pigment epithelial detachment (PED) successfully treated with intravitreal bevacizumab.

Design: Retrospective, observational case report.

Methods: The patient's records were reviewed.

Results: An 81-year-old man with history of age-related macular degeneration was seen on routine follow-up examination with an asymptomatic PED temporal to the macula in the right eye and visual acuity of 20/40. The patient was observed. Ten months later, the patient was found to have decreased vision to 20/80 and massive enlargement of the PED, with extension from the temporal equator into the macula. Optical coherence tomography of the macula showed a PED with overlying intraretinal cysts. The patient was given injections of intravitreal bevacizumab for every 4 months (1.25 mg) with complete resolution of the PED and return to baseline visual acuity of 20/40.

Conclusion: Giant PED secondary to exudative age-related macular degeneration can be successfully treated with intravitreal bevacizumab.

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http://dx.doi.org/10.1097/ICB.0b013e31817f2e1bDOI Listing

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