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Engaging dystonia networks with subthalamic stimulation.
Proc Natl Acad Sci U S A
January 2025
Center for Brain Circuit Therapeutics, Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115.
Deep brain stimulation is an efficacious treatment for dystonia. While the internal pallidum serves as the primary target, recently, stimulation of the subthalamic nucleus (STN) has been investigated. However, optimal targeting within this structure and its surroundings have not been studied in depth.
View Article and Find Full Text PDFUnusual Upper Cervical Spine Disorder and Non-traumatic Atlantoaxial Rotatory Fixation in an Adult: A Case Report.
Cureus
December 2024
Department of Orthopedic Surgery, Fujimi-Kogen Hospital, Fujimi-Kogen Medical Center, Fujimi, JPN.
This study reports on an extremely rare case of non-traumatic atlantoaxial rotatory fixation (AARF) in an adult. Although there are numerous reports on traumatic AARF in adults, those on non-traumatic AARFs are limited. We present the case of a 25-year-old woman who developed neck pain with a limited range of motion (ROM) that began upon waking without any particular inducement.
View Article and Find Full Text PDFAcute suppurative thyroiditis in a child secondary to pyriform sinus fistula: From single case to systematic review.
Int J Pediatr Otorhinolaryngol
December 2024
Department of Clinical and Experimental Medicine, Section of Pediatrics and Child Neuropsychiatry, Hospital "Policlinico G. Rodolico", Catania, Italy. Electronic address:
Acute suppurative thyroiditis (AST), a rare yet potentially life-threatening infection, comprises less than 1 % of neck pathologies and requires prompt treatment. Symptoms range from neck pain and fever to dysphagia and possible abscess formation. Broad-spectrum antibiotics are the primary treatment; however, surgical drainage may be necessary for abscesses to prevent systemic infection.
View Article and Find Full Text PDFAcute Torticollis Reaction Following Metoclopramide Use in a Pediatric Patient: A Comprehensive Case Report and Appraisal of Current Knowledge.
Int Med Case Rep J
December 2024
Faculty of Medicine, Mogadishu University, Mogadishu, Somalia.
Dopamine receptor antagonists like metoclopramide are frequently used in a variety of clinical contexts to treat gastrointestinal disorders and control nausea and vomiting. However, it is associated with a high incidence of extrapyramidal side effects (EPS) in children, including dystonic movements and torticollis. This is the instance of a 9-year-old girl who developed abnormal movements of the neck and tongue, along with torticollis, within 48 hours of receiving intravenous metoclopramide for gastroenteritis.
View Article and Find Full Text PDFTorticollis as an early manifestation of basilar invagination in a paediatric patient.
BMJ Case Rep
December 2024
McMaster Children's Hospital/ Hamilton Health Sciences, Hamilton, Ontario, Canada.
This case report describes the clinical journey of a male patient in early childhood with developmental delay, failure to thrive, worsening right-sided head tilt torticollis and regression of motor skills with spasticity of the lower limbs. The case was complex due to the early onset and gradually worsening symptoms, including a decline in established motor milestones. Genetic testing to investigate the delayed neurodevelopment revealed a variant that did not fully explain the patient's phenotype.
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