Purpose: To report the effect of intravitreal bevacizumab in type 2 idiopathic macular telangiectasia (type 2 IMT).

Design: Interventional case report.

Methods: A 51 year-old female patient with type 2 IMT presented with gradual visual deterioration and reading difficulties. In one affected eye, two intravitreal bevacizumab injections were performed with a four weeks interval. Examinations included ETDRS visual acuity, slit-lamp biomicroscopy, digital fluorescein angiography, optical coherence tomography (OCT) and microperimetry at baseline and during a 12-week review period.

Results: Following treatment the patient noted a visual improvement particularly during reading. On angiography a reduction in size and intensity of the hyperfluorescent area was recorded and the retinal sensitivity improved on microperimetry.

Conclusions: In absence of other efficacious therapeutic modalities, the observations indicate a beneficial therapeutic effect of intravitreal bevacizumab in type2-IMT, and implicate a pathophysiological role of VEGF in this disease entity.

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http://dx.doi.org/10.1097/ICB.0b013e31809ed9b6DOI Listing

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