Acute unilateral toxoplasma retinochoroiditis associated with adalimumab, a tumor necrosis factor-α antagonist.

Retin Cases Brief Rep

Massachusetts Eye Research and Surgery Institution, Cambridge, Massachusetts.

Published: January 2015

Purpose: The purpose of this study was to report a case of a patient with unilateral toxoplasma retinochoroiditis while on treatment with adalimumab, an anti-tumor necrosis factor α agent for ulcerative colitis.

Methods: This is a descriptive case report.

Results And Discussion: In addition to the patient with toxoplasma retinochoroiditis, there is one published report of two patients who developed toxoplasma chorioretinitis while on anti-tumor necrosis factor α therapy for rheumatoid arthritis: one was on adalimumab and methotrexate and the other one was on etanercept and methotrexate.

Conclusion: The authors need to be aware of this potentially vision threatening risk with anti-tumor necrosis factor α therapy.

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Source
http://dx.doi.org/10.1097/ICB.0b013e3182790dbdDOI Listing

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