Purpose: The purpose of this study is to describe a presumed case of Epstein-Barr virus (EBV) infection of the retina in a 65-year-old female with sudden bilateral vision loss.
Methods: Diagnostic vitreous biopsy of the left eye was performed to test for EBV and other known infectious causes of retinitis and evaluate vitreous cells.
Results: Serologic EBV testing was positive. Vitreous polymerase chain reaction viral DNA testing was positive for EBV, but negative for herpes-simplex virus, varicella-zoster virus, cytomegalovirus, and toxoplasma gondii. Histopathologic analysis of vitreous cells revealed atypical lymphocytes.
Conclusions: Epstein-Barr virus may be a cause of retinal disease. Awareness of this severe ocular complication may enable prompt diagnosis and treatment of future cases, and promote greater investigation into its disease prevalence.
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