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Association between a history of mental illness and the risk of systemic autoimmune rheumatic diseases: a nationwide, population-based case-control study.
Clin Rheumatol
February 2025
Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
Objective: Patients with systemic autoimmune rheumatic diseases (SARD) are at risk of mental illness, but whether mental illnesses are risk factors for SARD, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Sjögren's syndrome (SS), systemic sclerosis (SSc), dermatomyositis (DM)/polymyositis (PM), are still unknown. Therefore, we aim to address the association between a history of mental illnesses and the risk of SARD using a population-based database.
Methods: We used the 2000-2020 Taiwanese National Health Insurance Research Database in this case-control study.
Polymyositis-Like Myopathy With Anti-PL-12 Antibody Positivity and Coexisting Antiphospholipid Syndrome: Diagnostic and Management Challenges in the Absence of Systemic Features.
Cureus
January 2025
Medicine/Rheumatology, Hospital Corporation of America (HCA) Westside Regional Medical Center, Plantation, USA.
Polymyositis-like inflammatory myopathies are a rare subset of idiopathic inflammatory myopathies (IIMs) characterized by proximal muscle weakness, elevated muscle enzymes, and immune-mediated skeletal muscle damage. These conditions are often associated with myositis-specific autoantibodies (MSAs), such as anti-alanyl-tRNA synthetase antibody (anti-PL-12), which define subtypes like anti-synthetase syndrome. We present the case of a 50-year-old female patient with progressive proximal muscle weakness, elevated creatine kinase and aldolase levels, and serological evidence of anti-PL-12 antibodies.
View Article and Find Full Text PDFDermatomyositis as the First Manifestation of Nasopharyngeal Carcinoma-A Rare Case Report.
Medicina (Kaunas)
February 2025
Military Medical Academy, Faculty of Medicine, University of Defense, Crnotravska 17, 11000 Belgrade, Serbia.
Nasopharyngeal carcinoma (NPC) with paraneoplastic dermatomyositis (DM) is an exceptionally rare clinical phenomenon, particularly among European populations. This case report details a 46-year-old woman initially diagnosed with DM, later confirmed to have NPC. Such an association is more frequently documented in Asian populations, highlighting its unique presentation in this case.
View Article and Find Full Text PDF[A case of vedolizumab treatment for refractory juvenile dermatomyositis with secondary intestinal perforation].
Zhonghua Er Ke Za Zhi
March 2025
Department of Pediatric Rheumatology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Inflammatory myopathy with abundant macrophage [IMAM]: Systemic analysis and pathological approach to distinguish it from dermatomyositis.
J Neuromuscul Dis
February 2025
Department of Neurology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Background: Inflammatory myopathy with abundant macrophage [IMAM] is marked by macrophage infiltration and muscle fibers damage, resembling dermatomyositis [DM] but with unique pathology. Its mechanism remains unclear. Our study focused on exploring the clinicopathological characteristics, underlying pathogenic mechanisms, and the challenges in diagnosing and managing IMAM.
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