Current standard of treatment for chronic hepatitis C virus infection requires the use of pegylated interferon plus ribavirin. Treatment with these two agents has been associated with numerous side effects, which frequently include dermatologic eruptions. We report a cutaneous eruption associated with interferon having clinical presentation of erythema annulare centrifugum. The eruption occurred within days of the first interferon injection and repeatedly flared following subsequent injections. Our patient was able to continue therapy without interruption, while managing the reaction with topical corticosteroid and oral antihistamine. We conclude that this is a benign cutaneous eruption associated with interferon which can be managed without discontinuing treatment for hepatitis C.
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http://dx.doi.org/10.4081/dr.2013.e1 | DOI Listing |
Radiol Case Rep
March 2025
Department of Pediatric Dentistry, Faculty of Dental Medicine, Mohammed V University In Rabat, Morocco.
Teeth, either erupted or impacted, that exceed the normal count are known as supernumerary teeth. They can appear unilaterally or bilaterally, singly or in multiples, and may be located anywhere in both dental arches. Multiple permanent impacted supernumerary teeth are uncommon and are often associated to syndromes but can be idiopathic.
View Article and Find Full Text PDFJ Adv Periodontol Implant Dent
October 2024
Dental School, Universidad Europea de Madrid, Madrid, Spain.
Dental implant placement in the esthetic zone is associated with challenges for clinicians. The best esthetic outcome of this procedure can be obtained through precise management of hard and soft tissue. Orthodontic forced eruption (OFE) has presented an alternative approach to augment hard and soft tissues, which can be applied rapidly or slowly.
View Article and Find Full Text PDFClin Transl Sci
January 2025
Department of Pharmacy, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Targeted therapy and immunotherapy drugs for oncology have greater efficacy and tolerability than cytotoxic chemotherapeutic drugs. However, the cutaneous adverse drug reactions associated with these newer therapies are more common and remain poorly predicted. An effective prediction model is urgently needed and essential.
View Article and Find Full Text PDFActa Derm Venereol
January 2025
Toxirel Investigation Group, Alicante Spain; Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain; Department of Dermatology, Dr. Balmis University General Hospital, Alicante, Spain.
Cutaneous immune-related adverse events (cirAEs) may be associated with tumoral response and survival in patients using immune checkpoint inhibitors, but this relationship remains unclear because previous reports on the topic have various limitations. The purpose of this study was to examine the association of cirAEs with overall survival and progression-free survival in patients starting immune checkpoint inhibitors. A prospective observational study was conducted in a Spanish tertiary care hospital, including participants between March 2020 and May 2022.
View Article and Find Full Text PDFSci Rep
January 2025
Departamento de Ciencia de Alimentos y Biotecnología, Facultad de Ingeniería Química y Agroindustria, Escuela Politécnica Nacional (EPN), 170143, Quito, Ecuador.
Throughout history, food has played a fundamental role in the development of societies. An understanding of the diets of different cultures and their impact on health can provide valuable insights into their lifestyle. The identification of the animal remains found within two vessels is reported and, in addition, an assessment of whether the diet and soil composition of the period may be associated with toxic elements was carried out.
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