Up to 18% of patients submitted to cholecystectomy had concomitant common bile duct stones. To avoid serious complications, these stones should be removed. There is no consensus about the ideal management strategy for such patients. Traditionally, open surgery was offered but with the advent of endoscopic retrograde cholangiopancreatography (ERCP) and laparoscopic cholecystectomy (LC) minimally invasive approach had nearly replaced laparotomy because of its well-known advantages. Minimally invasive approach could be done in either two-session (preoperative ERCP followed by LC or LC followed by postoperative ERCP) or single-session (laparoscopic common bile duct exploration or LC with intraoperative ERCP). Most recent studies have found that both options are equivalent regarding safety and efficacy but the single-session approach is associated with shorter hospital stay, fewer procedures per patient, and less cost. Consequently, single-session option should be offered to patients with cholecysto-choledocholithiaisis provided that local resources and expertise do exist. However, the management strategy should be tailored according to many variables, such as available resources, experience, patient characteristics, clinical presentations, and surgical pathology.
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http://dx.doi.org/10.3748/wjg.v20.i41.15144 | DOI Listing |
Int J Spine Surg
March 2025
NeuroSpine Surgery Research Group (NSURG), Randwick, Australia.
Background: Uniportal spine endoscopy is a minimally invasive technique gaining widespread popularity, but fluid insufflation during the procedure poses risks of neurological deterioration. The present study examines these risks through a case series and literature review.
Methods: A review of the literature was conducted to identify reported complications related to fluid insufflation.
Int J Pharm
March 2025
Bioinformatics Center of AMMS, Beijing, People's Republic of China. Electronic address:
Traditional mRNA vaccine formulation loaded by lipid nanoparticle (mRNA-LNP) has several shortcomings in clinical application, including the need for cryopreservation, discomfort associated with intramuscular injections, and the risk of liver aggregation. Dissolvable microneedles (DMNs), as a novel transdermal drug delivery platform, can overcome the skin barrier to deliver drugs directly into the skin in a minimally invasive manner. However, mRNA-LNP is unstable and easily degraded during the solidification of DMN.
View Article and Find Full Text PDFUltraschall Med
March 2025
Department of Neonatology, University Medical Centre Mannheim, Mannheim, Germany.
To investigate the correlation between different prenatal imaging techniques in congenital diaphragmatic hernia (CDH) and their prognostic value.209 fetuses with CDH were enrolled in this retrospective cohort study. The prenatal ultrasound-based and MRI-based (MRI: magnetic resonance imaging) observed-to-expected lung-to-head ratio (o/e-LHR) and MRI-based relative fetal lung volume (rFLV) were evaluated and compared.
View Article and Find Full Text PDFAm J Obstet Gynecol
March 2025
Division of Gynecology and Obstetrics, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Objective: To assess the diagnostic accuracy of current hysteroscopic criteria compared with histopathological analysis (with or without additional immunohistochemistry) for the detection of chronic endometritis.
Data Sources: MEDLINE, Scopus, SciELO, Embase, ClinicalTrials.gov, Cochrane Central Register of Controlled Trials, LILACS, conference proceedings, and international controlled trials registries were searched without date limit or language restrictions.
Gan To Kagaku Ryoho
February 2025
Dept. of Digestive Surgery, Kyoto First Red Cross Hospital.
Robotic gastrectomy is a safe and minimally invasive approach that may reduce the risk of complications in patients with severely impaired pulmonary function. Here, we report the successful treatment of an 80-year-old patient with gastric cancer and myasthenia gravis(MG)using perioperative respiratory rehabilitation and robotic gastrectomy with D2 lymphadenectomy. Patients with gastric cancer and severe pulmonary dysfunction are at a risk of postoperative respiratory disorders, including severe pneumonia.
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