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Fixation-related potentials during a virtual navigation task: The influence of image statistics on early cortical processing.
Atten Percept Psychophys
January 2025
U.S. DEVCOM Army Research Laboratory, Humans in Complex Systems, Aberdeen Proving Ground, MD, USA.
Historically, electrophysiological correlates of scene processing have been studied with experiments using static stimuli presented for discrete timescales where participants maintain a fixed eye position. Gaps remain in generalizing these findings to real-world conditions where eye movements are made to select new visual information and where the environment remains stable but changes with our position and orientation in space, driving dynamic visual stimulation. Co-recording of eye movements and electroencephalography (EEG) is an approach to leverage fixations as time-locking events in the EEG recording under free-viewing conditions to create fixation-related potentials (FRPs), providing a neural snapshot in which to study visual processing under naturalistic conditions.
View Article and Find Full Text PDFThe outcomes of the obesity paradox in pulmonary embolism: a study of the national inpatient sample database from 2016 to 2020.
Ann Hematol
January 2025
Internal Medicine- Wayne State University School of Medicine, Rochester Hills, Michigan, USA.
The "obesity paradox" suggests that, despite a higher baseline risk for adverse health outcomes, obese patients can experience a lower complication and mortality rate in conditions such as pulmonary embolisms (PE). This study aims to examine the association between obesity and inpatient outcomes of PE patients, utilizing the data from the National Inpatient Sample (NIS) database. We conducted a retrospective study analysis of obese adult PE patients (aged ≥ 18) using the NIS database from 2016 to 2020.
View Article and Find Full Text PDFWorldwide epidemiology of paediatric multiple sclerosis: data from the Multiple Sclerosis International Federation Atlas of MS, third edition.
J Neurol Neurosurg Psychiatry
January 2025
Multiple Sclerosis International Federation, London, UK.
Background: Limited data are available on the global rates of paediatric multiple sclerosis. Here, we report on the estimated worldwide prevalence of paediatric MS.
Methods: We included paediatric prevalence data in 2020-2022 (Multiple Sclerosis International Federation Atlas of MS) and the prevalence of child neurologists (International Child Neurology Association).
Multi-SpinX: An advanced framework for automated tracking of mitotic spindles and kinetochores in multicellular environments.
Comput Biol Med
January 2025
Center for Cell Dynamics, School of Biological and Behavioural Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, United Kingdom; The Alan Turing Institute, London, NW1 2DB, United Kingdom. Electronic address:
SpinX, an AI-guided spindle tracking software, allows the 3-dimensional (3D) tracking of metaphase spindle movements in mammalian cells. Using over 900 images of dividing cells, we create the Multi-SpinX framework to significantly expand SpinX's applications: a) to track spindles and cell cortex in multicellular environments, b) to combine two object tracking (spindle with kinetochores marked by centromeric probes) and c) to extend spindle tracking beyond metaphase to prometaphase and anaphase stages where spindle morphology is different. We have used a human-in-the-loop approach to assess our optimisation steps, to manually identify challenges and to build a robust computational pipeline for segmenting kinetochore pairs and spindles.
View Article and Find Full Text PDFLearning Transversus Abdominis Activation in Older Adults with Chronic Low Back Pain Using an Ultrasound-Based Wearable: A Randomized Controlled Pilot Study.
J Funct Morphol Kinesiol
January 2025
Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13347 Berlin, Germany.
: Chronic low back pain (CLBP) is prevalent among older adults and leads to significant functional limitations and reduced quality of life. Segmental stabilization exercises (SSEs) are commonly used to treat CLBP, but the selective activation of deep abdominal muscles during these exercises can be challenging for patients. To support muscle activation, physiotherapists use biofeedback methods such as palpation and ultrasound imaging.
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