AI Article Synopsis
- Metal and metalloid exposure is unavoidable in daily life and can lead to toxicity in humans.
- Recent advancements in analytical techniques have shifted from older methods to more sophisticated multi-element techniques, particularly inductively coupled plasma mass spectrometry (ICP-MS).
- ICP-MS is crucial in clinical and forensic toxicology for analyzing various biological samples, including blood, urine, and tissues, to assess metal toxicity in humans.
Article Abstract
As metal/metalloid exposure is inevitable owing to its omnipresence, it may exert toxicity in humans. Recent advances in metal/metalloid analysis have been made moving from flame atomic absorption spectrometry and electrothermal atomic absorption spectrometry to the multi-elemental inductively coupled plasma (ICP) techniques as ICP atomic emission spectrometry and ICP-MS. ICP-MS has now emerged as a major technique in inorganic analytical chemistry owing to its flexibility, high sensitivity and good reproducibility. This in depth review explores the ICP-MS metallic profile in human toxicology. It is now routinely used and of great importance, in clinical toxicology and forensic toxicology to explore biological matrices, specifically whole blood, plasma, urine, hair, nail, biopsy samples and tissues.
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| http://dx.doi.org/10.4155/bio.14.190 | DOI Listing |
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