Background: the factors that moderate decline in physical functioning as death approaches are understudied. This study aimed to assess death-related decline in global quality of life (QoL) and physical functioning and to test whether baseline QoL moderates terminal decline in physical functioning.
Methods: four thousand six hundred and fifty-one decedents from the Women's Health Initiative Study (WHI) rated QoL and physical functioning each year throughout 5 years of follow-up.
Results: both QoL and physical functioning showed a steeper decline as a function of years to death than as a function of chronological age. Moreover, decedents with higher QoL at baseline showed a less steep decline in physical functioning as death approached than those with lower QoL at baseline.
Conclusion: although QoL strongly decreases across the terminal years, its beneficial influence on physical functioning is evident till the very end of life.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411222 | PMC |
| http://dx.doi.org/10.1093/ageing/afu176 | DOI Listing |
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