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A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization. | LitMetric
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A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization.

Benjamin D Fairbanks Michael P Schwartz Alexandra E Halevi Charles R Nuttelman Christopher N Bowman Kristi S Anseth

Adv Mater

Department of Chemical and Biological Engineering and the Howard Hughes Medical Institute University of Colorado Boulder, CO 80309-0424 (USA).

Published: December 2009

Step-growth, radically mediated thiol-norbornene photopolymerization is used to create versatile, stimuli-responsive poly(ethylene glycol)-co-peptide hydrogels The reaction is cytocompatible and allows for the encapsulation of human mesenchymal stem cells with a viability greater than 95%. Cellular spreading is dictated via three-dimensional biochemical photopatterning.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226179PMC
http://dx.doi.org/10.1002/adma.200901808DOI Listing

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