Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia.

Leukemia

1] Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany [2] Center of Integrated Oncology, University Hospital of Cologne, Cologne, Germany [3] Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University Hospital of Cologne, Cologne, Germany.

Published: April 2015

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http://dx.doi.org/10.1038/leu.2014.320	DOI Listing

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