Objective: To determine the prevalence, location, mechanism, and characteristics of peripheral nerve injury (PNI) in trauma patients.
Material And Methods: A retrospective study of medical records with PNI diagnosis secondary to trauma in the period of 2008-2012. The following information was collected: gender, age, occupation, anatomic location, affected nerve, mechanism of injury, degree of injury, costs, and hospitalization time.
Results: The prevalence of PNI is 1.12%. The location of the nerve injury was 61% upper limb, the highest incidence was presented to the brachial plexus (35%) and ulnar nerve (18%). The mechanism of the lesion was sharp injury (19%).
Discussion: The PNI are commonly present in people of a productive age. Neurotmesis was the most frequent degree of lesion. The patients stayed at hospital 2.51 ± 1.29 days and the average cost was 12,474.00 Mexican pesos ± 5,595.69 (US$ 1,007.54 ± 452.21) for one nerve injury.
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JBJS Rev
November 2024
Division of Plastic and Reconstructive Surgery, University of Colorado School of Medicine, Anschutz Medical Center, Aurora, Colorado.
Background: Modern nerve-to-nerve transfers are a significant advancement in peripheral nerve surgery. Nerve transfers involve transferring donor nerves or branches to recipient nerves close to the motor end unit, leading to earlier reinnervation and preservation of the musculotendinous units in proximal nerve injuries. After nerve reinnervation, function may be superior to traditional tendon transfer techniques in terms of strength and independent motion.
View Article and Find Full Text PDFJ Am Acad Orthop Surg
November 2024
From the Department of Hand and Reconstructive Microsurgery, National University Health System, Singapore (Lee), the Department of Orthopedic Surgery (Sammarco), the Department of Neurosurgery (Spinner), Mayo Clinic, Rochester, MN, and the Division of Hand and Microvascular Surgery, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN (Shin).
Painful neuromas are a complex clinical condition that results in notable disability and functional impairment after injury to a peripheral nerve. When regenerating axons lack a distal target, they form a stump neuroma. Up to 60% of neuromas are painful because of mechanical sensitivity and crosstalk between nerve fibers.
View Article and Find Full Text PDFMater Today Bio
February 2025
Department of Urology, Jiangnan University Affiliated Hospital, Medical College of Jiangnan University, Wuxi 214125, China.
Currently, most peripheral nerve injuries are incurable mainly due to excessive reactive oxygen species (ROS) generation in inflammatory tissues, which can further exacerbate localized tissue injury and cause chronic diseases. Although promising for promoting nerve regeneration, stem cell therapy still suffers from abundant intrinsic limitations, mainly including excessive ROS in lesions and inefficient production of growth factors (GFs). Biomaterials that scavenge endogenous ROS and promote GFs secretion might overcome such limitations and thus are being increasingly investigated.
View Article and Find Full Text PDFPlast Surg (Oakv)
January 2025
Division of Plastic and Reconstructive Surgery, Saint Louis University Hospital, St. Louis, MO, USA.
Brachial plexus birth injury (BPBI) is a condition affecting newborns and involves damage to the nerve fibers compromising the brachial plexus during birth. Although most newborns recover spontaneously, a large subset require surgery to regain function, and others will have permanent disability despite intervention. Deciding when to pursue surgical intervention remains a challenge for clinicians treating BPBI.
View Article and Find Full Text PDFFront Neurol
December 2024
The Second School of Clinical Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.
Objective: Sciatic nerve injuries often lead to severe pain and motor dysfunction, causing serious impact on patients' quality of life. Acupuncture, as one of the main therapies in traditional Chinese medicine, is gradually gaining attention in the field of nerve injury due to its potential role in pain relief and nerve repair. Bibliometric and scientific knowledge mapping methods were employed to analyze the current research status, hotspots, and development trends of acupuncture for sciatic nerve injury (SNI) over the past decade.
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