Effect of tetracycline HCl in the treatment of chronic periodontitis - A clinical study.

J Int Soc Prev Community Dent

Department of Preventive and Community Dentistry, Vyas Dental College, Jodhpur, Rajasthan, India.

Published: September 2014

AI Article Synopsis

  • The study aimed to assess the effectiveness of using tetracycline fibers alongside scaling and root planing in treating chronic periodontitis compared to scaling and root planing alone.
  • Conducted on 100 patients with chronic periodontitis, the researchers employed a split-mouth technique to evaluate the outcomes of both treatments.
  • Results showed that the combination treatment with tetracycline fibers led to a greater reduction in pocket depth and improved clinical attachment levels compared to scaling and root planing alone over a 3-month period.

Article Abstract

Objective: This study was aimed to evaluate the efficacy of the adjunctive use of tetracycline fibers (Periodontal Plus AB(®)) as a local drug delivery with scaling and root planing, as compared with the results of one episode of scaling and root planing for the treatment of chronic periodontitis.

Materials And Methods: The effectiveness of Periodontal Plus AB (tetracycline fiber) was assessed in 100 patients suffering from chronic periodontitis using split-mouth technique.

Statistical Analysis: The relative efficacy of the two treatment modalities was evaluated using the paired Student's t-test, and the comparative evaluation between the two groups was done using the independent Student's t-test.

Results: Significant improvement was found in all the variables, including reduction in pocket depth and gain in clinical attachment level, in both test and control groups in 3 months, which was statistically significant. Mean reduction in pocket depth and gain in clinical attachment level were more in test than in control group.

Conclusion: Tetracycline fiber therapy along with scaling and root planing improves the healing outcome, namely, reduction in pocket depth and gain in clinical attachment level, when compared to scaling and root planing alone.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209612PMC
http://dx.doi.org/10.4103/2231-0762.142011DOI Listing

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