Bottlenose dolphins performing echolocation tasks at long ranges may utilize a transmission mode where bursts, or "packets," of echolocation clicks are emitted rather than single clicks. The clicks within each packet are separated by time intervals well below the two-way travel time, while the packets themselves are emitted at intervals greater than the two-way travel time. Packet use has been shown to increase with range; however, the exact function of packets and the advantages gained by their utilization remain unknown. In this study, the capability for dolphins to utilize multi-echo processing within packets of echoes was investigated by manipulating the number of available echoes within each packet as a dolphin performed a long-range echolocation task. The results showed an improvement in detectability with an increase in the number of echoes in each packet and suggest that packet use is an adaptation to allow multi-echo processing at long ranges without introducing range ambiguity.
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http://dx.doi.org/10.1121/1.4898043 | DOI Listing |
Front Neurol
December 2024
Department of Neurology, Headache Outpatient Clinic, Medical University of Innsbruck, Innsbruck, Austria.
Background: There is evidence that iron metabolism may play a role in the underlying pathophysiological mechanism of migraine. Studies using (=1/ ) relaxometry, a common MRI-based iron mapping technique, have reported increased values in various brain structures of migraineurs, indicating iron accumulation compared to healthy controls.
Purpose: To investigate whether there are short-term changes in during a migraine attack.
Eur Radiol
December 2024
Department of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy.
Objectives: To develop a deep-learning model for supervised classification of myocardial iron overload (MIO) from magnitude T2* multi-echo MR images.
Materials And Methods: Eight hundred twenty-three cardiac magnitude T2* multi-slice, multi-echo MR images from 496 thalassemia major patients (285 females, 57%), labeled for MIO level (normal: T2* > 20 ms, moderate: 10 ≤ T2* ≤ 20 ms, severe: T2* < 10 ms), were retrospectively studied. Two 2D convolutional neural networks (CNN) developed for multi-slice (MS-HippoNet) and single-slice (SS-HippoNet) analysis were trained using 5-fold cross-validation.
Front Hum Neurosci
November 2024
Section on Cognitive Neuropsychology, Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, United States.
Understanding brain-behavior relationships is the core goal of cognitive neuroscience. However, these relationships-especially those related to complex cognitive and psychopathological behaviors-have recently been shown to suffer from very small effect sizes (0.1 or less), requiring potentially thousands of participants to yield robust findings.
View Article and Find Full Text PDFFluids Barriers CNS
November 2024
Interdisciplinary Institute of Neuroscience and Technology and Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, China.
Background: The choroid plexus (CP) plays a crucial role in cerebrospinal fluid (CSF) production and brain homeostasis. However, non-invasive imaging techniques to assess its function remain limited. This study was conducted to develop a novel, contrast-agent-free MRI technique, termed relaxation-exchange magnetic resonance imaging (REXI), for evaluating CP-CSF water transport, a potential biomarker of CP function.
View Article and Find Full Text PDFMagn Reson Med
November 2024
Department of Radiology, Weill Cornel Medicine, New York, New York, USA.
Purpose: Myelin quantification is used in the study of demyelination in neurodegenerative diseases. A novel noninvasive MRI method, Microstructure-Informed Myelin Mapping (MIMM), is proposed to quantify the myelin volume fraction (MVF) from a routine multi-gradient echo sequence (mGRE) using a multiscale biophysical signal model of the effects of microstructural myelin and iron.
Theory And Methods: In MIMM, the effects of myelin are modeled based on the Hollow Cylinder Fiber Model accounting for anisotropy, while iron is considered as an isotropic paramagnetic point source.
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