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De novo Assembly and Analysis of the Northern Leopard Frog Rana pipiens Transcriptome. | LitMetric

De novo Assembly and Analysis of the Northern Leopard Frog Rana pipiens Transcriptome.

J Genomics

1. Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska 68182, USA; ; 4. Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.

Published: November 2014

AI Article Synopsis

Article Abstract

The northern leopard frog Rana (Lithobates) pipiens is an important animal model, being used extensively in cancer, neurology, physiology, and biomechanical studies. R. pipiens is a native North American frog whose range extends from northern Canada to southwest United States, but over the past few decades its populations have declined significantly and is now considered uncommon in large portions of the United States and Canada. To aid in the study and conservation of R. pipiens, this paper describes the first R. pipiens transcriptome. The R. pipiens transcriptome was annotated using Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Eukaryotic Orthologous Groups (KOG). Differential expression analysis revealed universal and tissue specific genes, and endocrine-related genes were identified. Transcriptome assemblies and other sequence data are available for download.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218947PMC
http://dx.doi.org/10.7150/jgen.9760DOI Listing

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