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Prehospital lactate analysis in suspected sepsis improves detection of patients with increased mortality risk: an observational study.
Crit Care
January 2025
Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Background: Rapid, adequate treatment is crucial to reduce mortality in sepsis. Risk stratification scores used at emergency departments (ED) are limited in detecting all septic patients with increased mortality risk. We assessed whether the addition of prehospital lactate analysis to clinical risk stratification tools improves detection of patients with increased risk for rapid deterioration and death in sepsis.
View Article and Find Full Text PDFObjectives: Prehospital notifications (pre-alerts) enable emergency department (ED) staff to prepare for the arrival of patients requiring a time-critical response. Effective communication of the pre-alert is key to enabling the ED to prepare appropriately, but evidence on communication practices is lacking. We undertook qualitative research to understand how pre-alert communication may be improved to optimise the ED response for pre-alerted patients.
View Article and Find Full Text PDFDoes a Simple Blood Gas Analysis and the Clinical Impression Predict Trauma-Induced Coagulopathy?
Hamostaseologie
January 2025
Department of Anaesthesiology and Intensive Care Medicine, Husum Hospital, Husum, Schleswig-Holstein, Germany.
Objectives: Trauma-induced coagulopathy (TIC) is common in severely injured patients and is associated with significant morbidity and mortality.
Method: The association of two parameters of blood gas analysis (hemoglobin [Hb], base excess [BE]) with standard coagulation tests (SCTs) and rotational thrombelastometry (ROTEM) using the database of the TraumaRegister DGU between 2015 and 2022 was studied. In a stepwise approach, the occurrence of a TIC, the correlations between Hb/BE levels and SCT, as well as ROTEM were calculated respectively.
A Systematic Literature Review of Trauma Systems: An Operations Management Perspective.
Adv Rehabil Sci Pract
January 2025
Consultant in Rehabilitation Medicine, National Rehabilitation Centre, Nottingham University Hospitals NHS Trust, UK.
Background: Trauma systems provide comprehensive care across various settings, from prehospital services to rehabilitation, integrating clinical and social care aspects. Established in the 1970s, these systems are pivotal yet under-researched in their operational management. This study aims to fill this gap by focussing on the integration of operations management (OM) techniques to enhance the efficiency and effectiveness of trauma systems.
View Article and Find Full Text PDFWater triggered injectable polylactic acid hydrogel based on zwitterionic sulfobetaine modification for incompressible bleeding and tissue anti-adhesion.
Mater Today Bio
February 2025
Institution of Disaster and Emergency Medicine, Tianjin University, Tianjin, 300072, China.
Massive blood loss is the main cause of prehospital trauma-related death, the development of rapid and effective hemostatic materials is imminent. Injectable hydrogels have the advantages of covering irregular bleeding sites and quickly closing the wound. However, its inherent viscosity can easily precipitate tissue adhesion and other complications.
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