Purpose: To evaluate the performance of the Elekta Agility multileaf collimator (MLC) for dynamic real-time tumor tracking.
Methods: The authors have developed a new control software which interfaces to the Agility MLC to dynamically program the movement of individual leaves, the dynamic leaf guides (DLGs), and the Y collimators ("jaws") based on the actual target trajectory. A motion platform was used to perform dynamic tracking experiments with sinusoidal trajectories. The actual target positions reported by the motion platform at 20, 30, or 40 Hz were used as shift vectors for the MLC in beams-eye-view. The system latency of the MLC (i.e., the average latency comprising target device reporting latencies and MLC adjustment latency) and the geometric tracking accuracy were extracted from a sequence of MV portal images acquired during irradiation for the following treatment scenarios: leaf-only motion, jaw + leaf motion, and DLG + leaf motion.
Results: The portal imager measurements indicated a clear dependence of the system latency on the target position reporting frequency. Deducting the effect of the target frequency, the leaf adjustment latency was measured to be 38 ± 3 ms for a maximum target speed v of 13 mm/s. The jaw + leaf adjustment latency was 53 ± 3 at a similar speed. The system latency at a target position frequency of 30 Hz was in the range of 56-61 ms for the leaves (v ≤ 31 mm/s), 71-78 ms for the jaw + leaf motion (v ≤ 25 mm/s), and 58-72 ms for the DLG + leaf motion (v ≤ 59 mm/s). The tracking accuracy showed a similar dependency on the target position frequency and the maximum target speed. For the leaves, the root-mean-squared error (RMSE) was between 0.6-1.5 mm depending on the maximum target speed. For the jaw + leaf (DLG + leaf) motion, the RMSE was between 0.7-1.5 mm (1.9-3.4 mm).
Conclusions: The authors have measured the latency and geometric accuracy of the Agility MLC, facilitating its future use for clinical tracking applications.
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http://dx.doi.org/10.1118/1.4899175 | DOI Listing |
Eur J Med Res
November 2024
Department of Radiotherapy, Tianjin Cancer Hospital Airport Hospital, Tianjin, 300308, People's Republic of China.
BMC Vet Res
September 2024
Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Alexandria University, Abees 10th Post Box: 22785, Alexandria, 21944, Egypt.
The study was focused on the anatomical characteristics of the Egyptian long-eared hedgehog's oral cavity by using gross and scanning electron microscopic examinations. The upper lip had an elongated T-shaped snout-like structure. The hard palate had a triangular rostral part (which had a semicircular area and a caudal ridged area with the first 3 or 4 ridges) and a caudal part (which contained seven or eight slightly oblique ridges with raphae).
View Article and Find Full Text PDFOrthod Craniofac Res
February 2025
Surgical, Medical and Dental Department, University of Modena and Reggio Emilia, Modena, Italy.
Objective: The aim of this randomized controlled trial (RCT) was to evaluate the spontaneous distorotation of upper first permanent molars and the transverse dentoalveolar changes on digital casts in growing patients following maxillary expansion treatment using either the Leaf Expander® or the rapid maxillary expander (RME), both anchored to the deciduous second molar.
Trial Design And Setting: This study was a two-arm, parallel-assignment, RCT with a dual-centre design conducted at two teaching hospitals in Italy.
Participants: Inclusion criteria included maxillary transverse deficiency, prepubertal development stage (cervical vertebra maturation stage [CVMS] 1-2) and early mixed dentition with fully erupted upper first permanent molars.
Orthod Craniofac Res
December 2024
Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.
BJR Case Rep
July 2024
Department of Radiology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Volumetric-modulated arc therapy (VMAT) with field-extended multi-isocentre irradiation (VMAT-FEMII) is an effective irradiation technique, particularly for large planning target volumes in the craniocaudal direction. A variety of treatment planning techniques have been reported to reduce the dosimetric impact. However, there is no guarantee that unexpected latent systematic errors would not occur.
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