AI Article Synopsis
- A patient with clinically amyopathic dermatomyositis (CADM) developed an autoantibody known as anti-CADM-140, which was linked to rapidly progressive interstitial lung disease (RP-ILD).
- High-resolution chest CT scans showed early signs of lung involvement occurring before the appearance of typical skin lesions associated with CADM.
- When doctors observe unexplained patchy peribronchial opacity on chest HRCT, they should consider the possibility of RP-ILD related to anti-CADM-140 autoantibodies.
Article Abstract
We herein report a patient with clinically amyopathic dermatomyositis (CADM) who developed anti-CADM-140 autoantibody in association with rapidly progressive interstitial lung disease (RP-ILD). Chest high-resolution computed tomography (HRCT) revealed early pulmonary involvement preceding typical cutaneous lesions. Primary lesions of patchy peribronchial opacity developed ground-glass opacity and consolidation with architectural distortion and traction bronchiectasis. The possibility of anti-CADM-140 autoantibody-associated RP-ILD should be considered when patchy peribronchial opacity of an unknown cause is visible on chest HRCT.
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| http://dx.doi.org/10.2169/internalmedicine.53.2769 | DOI Listing |
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