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Amplified by the decline in antibiotic discovery, the rise of antibiotic resistance has become a significant global challenge in infectious disease control. Extraintestinal (ExPEC), known to be the most common instigators of urinary tract infections (UTIs), represent such global threat. Novel strategies for more efficient treatments are therefore desperately needed.

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Molecular Epidemiological Characteristics of -Carrying ST-11 in Hospitalized Patients.

Infect Drug Resist

January 2025

Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.

Purpose: To investigate the molecular epidemiology and risk factors of carbapenem-resistant (CRKP) infection.

Patients And Methods: Patient's clinical data and CRKP strains were collected from November 2017 to December 2018 at a tertiary hospital in Wuhan, China. The antimicrobial susceptibilities, carbapenem-resistant genes, multi-locus sequence typing (MLST), homologous analysis, and risk factors for CRKP were determined.

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Multidrug resistant : A study on its pathogenesis and therapeutics.

Curr Res Microb Sci

December 2024

Department of Life Science, Guru Nanak Institute of Pharmaceutical Science and Technology, 157/F, Nilgunj Rd, Sahid Colony, Panihati, Kolkata, West Bengal 700114, India.

The overuse of antibiotics has led to the global dissemination of , an increasingly challenging nosocomial pathogen. This review explores the medical significance along with the diverse resistance ability of . Intensive care units (ICUs) serve as a breeding ground for , as these settings harbour vulnerable patients and facilitate the spread of opportunistic microorganisms.

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Background: Catheter associated urinary tract infection is the most common nosocomial infection that is associated with serious systemic infections that imply prolonged hospital stay, financial costs for hospitalization, and increased morbidity, and mortality. There is a dearth of evidence related to nurse's knowledge and practice of catheter associated urinary tract infection prevention in Oromia, Ethiopia. Determining the nurse's knowledge and preventive practice of catheter associated urinary tract infections and their associated factors is important for developing strategies of its prevention.

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The emergence of carbapenem-resistant pathogenic bacteria is a growing global public health concern. Carbapenem-resistant uropathogenic strains of can cause uncomplicated or complicated urinary tract infections, leading to a high risk of treatment failure and the spread of resistance determinants. The objectives of this 24-month study were to identify the prognostic characteristics of patients who were infected with carbapenem-resistant () and to create a tool to estimate the probability of a infection before having the complete results of a patient's antibiogram.

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