Correct return of the measuring beam is essential for laser interferometers to carry out measurement. In the actual situation, because the measured object inevitably rotates or laterally moves, not only the measurement accuracy will decrease, or even the measurement will be impossibly performed. To solve this problem, a novel orthogonal return method for linearly polarized beam based on the Faraday effect is presented. The orthogonal return of incident linearly polarized beam is realized by using a Faraday rotator with the rotational angle of 45°. The optical configuration of the method is designed and analyzed in detail. To verify its practicability in polarization interferometry, a laser heterodyne interferometer based on this method was constructed and precision displacement measurement experiments were performed. These results show that the advantage of the method is that the correct return of the incident measuring beam is ensured when large lateral displacement or angular rotation of the measured object occurs and then the implementation of interferometric measurement can be ensured.
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http://dx.doi.org/10.1063/1.4897520 | DOI Listing |
PLoS One
November 2024
Department of Resource Economics and Environmental Sociology, University of Alberta, Edmonton, Alberta, Canada.
As climate warming exacerbates wildfire risks, prompt wildfire detection is an essential step in designing an efficient suppression strategy, monitoring wildfire behavior and, when necessary, issuing evacuation orders. In this context, there is increasing demand for estimates of returns on wildfire investments and their potential for cost savings. Using fire-level data from Western Canada during 2015-2020, the paper associates variation in wildfire reporting delays with variation in suppression costs.
View Article and Find Full Text PDFJ Vet Med Educ
October 2024
School of Veterinary Medicine, Texas Tech University 7671 Evans Dr., Amarillo, TX 79109, USA.
Veterinary training programs rely on animal cadavers for a variety of important educational activities, yet ethical sourcing can present considerable challenges. Public sentiment has rendered traditional sources (e.g.
View Article and Find Full Text PDFChemistry
November 2024
Department of System Chemotherapy and Molecular Sciences, Division of Medicinal Frontier Sciences, Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto, 606-8501, Japan.
A robust, practical, and sustainable isomerization-suppressed peptide bond formation via acyl sulfonamide, a twisted amide, is disclosed. Tosyl isocyanate and pentafluorobenzyl bromide were applied in combination to activate the peptide C-terminus, which then reacted with an amine to yield an elongated peptide with high stereochemical purity. Careful analysis of NMR spectra of the active intermediate revealed the presence of an intramolecular hydrogen bond, suggesting that the hydrogen bond suppressed Cα-epimerization during amidation.
View Article and Find Full Text PDFAdv Mater
November 2024
Department of Bioengineering, University of Washington, Seattle, WA, 98105, USA.
Biomechanical contributions of the extracellular matrix underpin cell growth and proliferation, differentiation, signal transduction, and other fate decisions. As such, biomaterials whose mechanics can be spatiotemporally altered- particularly in a reversible manner- are extremely valuable for studying these mechanobiological phenomena. Herein, a poly(ethylene glycol) (PEG)-based hydrogel model consisting of two interpenetrating step-growth networks is introduced that are independently formed via largely orthogonal bioorthogonal chemistries and sequentially degraded with distinct recombinant sortases, affording reversibly tunable stiffness ranges that span healthy and diseased soft tissues (e.
View Article and Find Full Text PDFSci Rep
August 2024
Department of Mechanical and Process Engineering, ETH Zürich, 8092, Zürich, Switzerland.
Flow fluctuations have emerged as a promising hemodynamic metric for understanding of hemodynamics in intracranial aneurysms. Several investigations have reported flow instabilities using numerical tools. In this study, the occurrence of flow fluctuations is investigated using either Newtonian or non-Newtonian fluid models in five patient-specific intracranial aneurysms using high-resolution lattice Boltzmann simulation methods.
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