AI Article Synopsis
- The study tested the effectiveness of an integrative cognitive training program called REHACOP on improving cognition and functional abilities in Parkinson's disease patients.
- Forty-two participants with varying stages of Parkinson's were either assigned to the cognitive training group or a control group, and their progress was measured over three months.
- Results showed that participants in the REHACOP group had significant improvements in areas such as processing speed, visual memory, theory of mind, and overall functional disability compared to the control group, suggesting that cognitive training could be beneficial for these patients.
Article Abstract
Objectives: To examine the efficacy of an integrative cognitive training program (REHACOP) to improve cognition, clinical symptoms, and functional disability of patients with Parkinson disease (PD).
Methods: Forty-two patients diagnosed with PD in Hoehn & Yahr stages 1 to 3 were randomly assigned to either the cognitive training group (REHACOP) or the control group (occupational activities) for 3 months (3 sessions, 60 min/wk). Primary outcomes were change on processing speed, verbal memory, visual memory, executive functioning, and theory of mind. Secondary outcomes included changes on neuropsychiatric symptoms, depression, apathy, and functional disability. The trial was registered with clinicaltrials.gov (NCT02118480).
Results: No baseline group differences were found. Bootstrapped analysis of variance results showed significant differences in the mean change scores between the REHACOP group and control group in processing speed (0.13 [SE = 0.07] vs -0.15 [SE = 0.09], p = 0.025), visual memory (0.10 [SE = 0.10] vs -0.24 [SE = 0.09], p = 0.011), theory of mind (1.00 [SE = 0.37] vs -0.27 [SE = 0.29], p = 0.013), and functional disability (-5.15 [SE = 1.35] vs 0.53 [SE = 1.49], p = 0.012).
Conclusions: Patients with PD receiving cognitive training with REHACOP demonstrated statistically significant and clinically meaningful changes in processing speed, visual memory, theory of mind, and functional disability. Future studies should consider the long-term effect of this type of intervention. These findings support the integration of cognitive training into the standard of care for patients with PD.
Classification Of Evidence: This study provides Class II evidence that for patients with PD, an integrative cognitive training program improves processing speed, visual memory, theory of mind, and functional disability.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276404 | PMC |
| http://dx.doi.org/10.1212/WNL.0000000000001043 | DOI Listing |
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