Risk factor analysis of perioperative mortality after ruptured bleeding in hepatocellular carcinoma.

World J Gastroenterol

Hao-Ming Lin, Guo-Lin Li, Jun Min, Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou 510120, Guangdong Province, China.

Published: October 2014

Aim: To discuss strategies and prognosis for the emergency treatment of ruptured bleeding in primary hepatocellular carcinoma.

Methods: The retrospective analysis was performed by examining the emergency treatment experiences of 60 cases of ruptured bleeding in primary hepatocellular carcinoma. The treatment methods included surgical tumour resection, transcatheter arterial embolization (TAE) and non-surgical treatment. Univariate and multivariate analyses were performed to identify the risk factors that impacted 30-d mortality in the research groups.

Results: The 30-d mortality of all patients was 28.3% (n = 17). The univariate analysis showed that Child-Pugh C level liver function, shock, massive blood transfusion and large tumour volume were risk factors that influenced 30-d mortality. The multivariate analysis showed that shock and massive blood transfusion were independent risk factors that impacted the 30-d mortality of surgical resection. As for the TAE patients, larger tumour volume was a risk factor towards prognosis.

Conclusion: Radical resection and TAE therapy would achieve better results in carefully selected ruptured hepatocellular tumours.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209555PMC
http://dx.doi.org/10.3748/wjg.v20.i40.14921DOI Listing

Publication Analysis

Top Keywords

30-d mortality
16
ruptured bleeding
12
risk factors
12
risk factor
8
hepatocellular carcinoma
8
emergency treatment
8
bleeding primary
8
primary hepatocellular
8
factors impacted
8
impacted 30-d
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!