Persistent pain following groin hernia repair (PPGH) is seen in 2-4% of patients leading to functional and socioeconomic disability. A Danish research unit for PPHG was established in 2010 in collaboration with anaesthetists and surgeons. More than 140 patients have been examined with clinical and electrophysiological methods. Published data on 54 patients, treated with mesh removal and selective neurectomy, demonstrated that 65% patients experienced long-term reduction of pain. The PPHG unit is actively engaged in surgical and pharmacological research in order to improve treatment strategies.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Morphine-Induced Elevation of Reactive Oxygen Species Attenuates Chemotherapy Efficacy in Diverse Cancer Cell Types.
Curr Mol Med
January 2025
Department of Anesthesiology, Baoan Central Hospital of Shenzhen, Shenzhen, Guangdong Province, China.
Background: Morphine, a mu-opioid receptor (MOR) agonist commonly utilized in clinical settings alongside chemotherapy to manage chronic pain in cancer patients, has exhibited contradictory effects on cancer, displaying specificity toward certain cancer types and doses.
Objective: The aim of this study was to conduct a systematic assessment and comparison of the impacts of morphine on three distinct cancer models in a preclinical setting.
Methods: Viability and apoptosis assays were conducted on a panel of cancer cell lines following treatment with morphine, chemotherapy drugs alone, or their combination.
Multiple liver metastases of unknown origin: A case report.
World J Gastrointest Oncol
January 2025
Department of Hepatobiliary Pancreatic Surgery, Peking University First Hospital, Beijing 100034, China.
Background: The liver is the most common site of digestive system tumor metastasis, but not all liver metastases can be traced back to the primary lesions. Although it is unusual, syphilis can impact the liver, manifesting as syphilitic hepatitis with inflammatory nodules, which might be misdiagnosed as metastasis.
Case Summary: This case report involves a 46-year-old female who developed right upper abdominal pain and intermittent low fever that persisted for more than three months.
Electromagnetic navigation guided tailored lamino-pedicular intralesional marginal resection of recurrent sacral osteoblastoma: a case report.
J Spine Surg
December 2024
Department of Orthopaedic Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Background: Electromagnetic navigation (EMN) is an advanced technology increasingly utilized in orthopedic surgery for its ability to provide real-time intraoperative guidance. Its application in spinal surgery is evolving rapidly, particularly for complex cases like tumor lesions. Spinal osteoblastomas, characterized by their benign nature, primarily affect the posterior elements of the spine.
View Article and Find Full Text PDFAdult Mediastinal Lymphangioma Presenting As Persistent Chest Pain: A Case Report.
Cureus
December 2024
Obstetrics and Gynecology, First Health Cluster, Dammam, SAU.
Mediastinal lymphangiomas are rare benign tumors arising from lymphatic system malformations, most commonly seen in pediatric populations. In adults, they are exceedingly rare and present diagnostic challenges due to nonspecific symptoms and imaging overlap with other mediastinal masses. Diagnosis is typically based on imaging, including CT and MRI, with histopathology confirming the diagnosis.
View Article and Find Full Text PDFUse of Oral and Intravenous Tranexamic Acid in Total Knee Arthroplasty and Total Hip Arthroplasty Procedures.
Cureus
December 2024
General Orthopedics, Midwest Bone and Joint Center, Macon, USA.
Introduction: Tranexamic acid (TXA) is an antifibrinolytic drug commonly used in total knee arthroplasty (TKA). Intravenous (IV) and topical TXA therapy have been extensively studied and shown to reduce blood loss, length of hospital stay, and blood transfusion rates following TKA. Despite the extensive literature regarding IV and topical TXA in orthopedics, there is a current dearth of studies analyzing oral usage.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!