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The Dual Role of Cellular Senescence in Macrophages: Unveiling the Hidden Driver of Age-Related Inflammation in Kidney Disease.
Int J Biol Sci
January 2025
Research Center of Integrated Traditional Chinese and Western Medicine, the Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, 646000 Luzhou, China.
Aging is a complex biological process that involves the gradual decline of cellular, tissue, and organ functions. In kidney, aging manifests as tubular atrophy, glomerulosclerosis, and progressive renal function decline. The critical role of senescence-associated macrophage in diseases, particularly kidney diseases, is increasingly recognized.
View Article and Find Full Text PDFIn recent years, image processing technology has been increasingly studied on intelligent unmanned platforms, and the differences in the shooting environment during tobacco baking pose challenges to image processing algorithms. To address this problem, an ensemble multi-dimensional randomization network (EMRNet) for intelligent recognition of tobacco baking stage is proposed. The first is to obtain the tobacco leaf area during the baking process.
View Article and Find Full Text PDFEnlightening Hidden Nursing Care in Nurse-Led Clinics and See & Treat: An Observational Multicenter Protocol Study in Italy.
Nurs Rep
November 2024
Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
The limited and inconsistent adoption and regulation of nurse-led clinics (NLCs) and "See & Treat" (S&T) services in Italy needs to be explored considering their value towards patients' outcomes acknowledged in the literature. This study aims to explore the phenomenon of hidden nursing activities (HNAs) in these settings, hypothesizing that features and activities performed in these settings are heterogeneous across the country and widely underreported or attributed to other professionals than nurses. HNAs are hypothesized to be associated with a poor work environment climate and nurses' low job satisfaction.
View Article and Find Full Text PDFOptical approaches have made great strides towards the goal of high-speed, energy-efficient computing necessary for modern deep learning and AI applications. Read-in and read-out of data, however, limit the overall performance of existing approaches. This study introduces a multilayer optoelectronic computing framework that alternates between optical and optoelectronic layers to implement matrix-vector multiplications and rectified linear functions, respectively.
View Article and Find Full Text PDFRevealing hidden risks: in vitro analysis of PFAS hazards in Mytilus galloprovincialis gills and digestive gland.
J Hazard Mater
December 2024
Department of Biology, University of Aveiro, Aveiro 3810-193, Portugal; Centre for Environmental and Marine Studies (CESAM), University of Aveiro, Aveiro 3810-193, Portugal. Electronic address:
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals known for their persistence and bioaccumulation, leading to widespread environmental contamination. Despite their recognised environmental risks, particularly to aquatic wildlife, including marine invertebrates, detailed impact studies are limited. PFAS can be categorised according to the length of the compound chain, with short-chain PFAS announced as a safer alternative to the more commonly used long-chain PFAS.
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