Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189646 | PMC |
| http://dx.doi.org/10.5698/1535-7597-14.5.289 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Cognitive impairment in bilinguals with neurological diseases].
Zh Nevrol Psikhiatr Im S S Korsakova
December 2024
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia.
Bilingualism is widespread in the world and In Russia and in recent years has been actively considered within the framework of the cognitive reserve concept. The paper provides a review of articles studying cognitive functions in bilingual patients with neurological diseases. Cognitive disorders and dementia in bilinguals occur about 5 years later in comparison with those who speak only one language.
View Article and Find Full Text PDFMechanistic insights into Quetiapine's Protective effects on cognitive function and synaptic plasticity in epileptic rats.
Brain Res
December 2024
Ningxia Clinical Research Institute, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, Ningxia, PR China.
The study aimed to examine the effects of Quetiapine, an atypical antipsychotic medication with purported neuroprotective qualities, on cognitive function and synaptic plasticity in epileptic rats. This investigation also sought to elucidate the mechanisms by which quetiapine influences the activity of the cyclic adenylate response element binding protein (CREB)/brain-derived neurotrophic factor (BDNF) signaling pathway and metallomatrix proteinase-9 (MMP9) expression in the context of epilepsy. The epileptic model was induced in rats through the administration of pilocarpine, with normal rats serving as the control group.
View Article and Find Full Text PDFObjective: We examined people with epilepsy (PWE) regarding presenteeism, an aspect of reduced work productivity due to health-related issues despite physical presence, with a focus on epilepsy treatment and psychosocial factors.
Methods: We used data from 32,000 participants aged 16-83 years old that were obtained through a 2024 nationwide internet survey. The Work Functioning Impairment Scale, which measures "presenteeism," was used to compare participants with and without a history of epilepsy.
Objective: Functional MRI (fMRI) helps with the identification of eloquent cortex to assist with function preservation in patients who undergo epilepsy surgery. Language and memory tasks can even be used effectively in clinically involved pediatric patients. Most pediatric studies report on English speaking-only cohorts from English-dominant countries, yet languages other than English (LOEs) are increasingly prevalent in countries such as the US.
View Article and Find Full Text PDFIdentifying the Pathogenicity of a Novel NPRL3 Missense Mutation Using Personalized Cortical Organoid Model of Focal Cortical Dysplasia.
J Mol Neurosci
December 2024
Department of Neurosurgery, National Children's Medical Center (Shanghai), Children's Hospital of Fudan University, No.399 Wan Yuan Avenue, Minhang District, Shanghai, 201102, China.
Focal cortical dysplasia (FCD) II is a cortical malformation characterized by cortical architectural abnormalities, dysmorphic neurons, with or without balloon cells. Here, we systematically explored the pathophysiological role of the GATOR1 subunit NPRL3 variants including a novel mutation from iPSCs derived from one FCD II patient. Three FCD II children aged 0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!