Polyreactive autoantibodies able to bind double-stranded DNA are a characteristic of systemic lucus erytheamtosus. Here, David Isenberg and Yehuda Shoenfeld discuss the likelihood that DNA is the immunogen in this disorder, and review a number of cross-reactions that may underline the detection of the antibodies.
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| http://dx.doi.org/10.1016/0167-5699(87)90189-7 | DOI Listing |
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