The Canadian kidney paired donation program: a national program to increase living donor transplantation.

Transplantation

1 Renal Transplant Program, University Health Network, Toronto, Canada. 2 Renal Transplant Program, University of Manitoba, Winnipeg & Canadian Blood Services, Ottawa, Canada. 3 Department of Medicine and Laboratory Medicine, University of Alberta, Edmonton, Canada. 4 Canadian Blood Services, Ottawa, Canada. 5 Renal Transplant Program, St. Michael's Hospital, Toronto, Canada. 6 Division of Nephrology, University of British Columbia, St. Paul's Hospital, Vancouver, Canada. 7 Center for Health Evaluation and Outcomes Sciences, Vancouver, Canada. 8 Tuft's New England Medical Center, Boston, MA.

Published: May 2015

Background: Establishment of a national kidney paired donation (KPD) program represents a unique achievement in Canada's provincially organized health care system.

Methods: Key factors enabling program implementation included consultation with international experts, formation of a unique organization with a mandate to facilitate interprovincial collaboration, and the volunteer efforts of members of the Canadian transplant community to overcome a variety of logistical barriers.

Results: As of December 2013, the program had facilitated 240 transplantations including 10% with Calculated panel reactive antibody (cPRA) ≥97%. Unique features of the Canadian KPD program include participation of n = 55 nondirected donors, performance of only donor specific antibody negative transplants, the requirement for donor travel, and nonuse of bridge donors.

Conclusion: The national KPD program has helped maintain the volume of living kidney donor transplants in Canada over the past 5 years and serves as a model of inter-provincial collaboration to improve the delivery of health care to Canadians.

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Source
http://dx.doi.org/10.1097/TP.0000000000000455DOI Listing

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