An auto-catalytic domino reaction, presumably involving an aza-Michael reaction, proton transfer, and lactonization, furnishing α-(aminomethyl)-γ-butyrolactones in near quantitative yields and excellent diastereoselectivity is described.

Download full-text PDF

Source
http://dx.doi.org/10.1039/c4cc05765aDOI Listing

Publication Analysis

Top Keywords

diastereoselective synthesis
4
synthesis α-aminomethyl-γ-butyrolactones
4
α-aminomethyl-γ-butyrolactones catalyst-free
4
catalyst-free aminolactonization
4
aminolactonization auto-catalytic
4
auto-catalytic domino
4
domino reaction
4
reaction presumably
4
presumably involving
4
involving aza-michael
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!